| | North West Contractor Framework | Oldham | £2B |
| | Media Services | Liverpool | £1B |
| | Tail Spend Solution | Liverpool | £1B |
| | A2Dominion Group Commercial Contractor | London | £900M |
| | Collaborative Recruitment Services | London | £850M |
| | Managed Print Services for Apprenticeship and T Level Certificates | Manchester | £428M |
| | HS2 Phase 1 Stations: Interchange Station Two-Stage Design and Build and Framework Agreement | Birmingham | £370M |
| | Interchange Station Two-Stage Design and Build | Birmingham | £370M |
| | Disposable Medical Gloves (PPE) for Healthcare Workers for the Care of Patients With Suspected or Confirmed… | London | £312M |
| | Purchases of Examination Gloves (6N Nitrile, Vinyl, Latex) | Leeds | £312M |
| | Records Information Management, Digital Solutions and Associated Services (Lots 1-4) | Liverpool | £260M |
| | NHS National Pharmaceuticals Transition | Runcorn | £214M |
| | Dynamic Purchasing System for Retrofit Programme Delivery Services | Manchester | £208M |
| | Area 3 Maintenance and Response (M&R | Guildford | £204M |
| | En:Procure New Build Framework (North West & East Midlands) | Sheffield | £200M |
| | Extra Care Housing and Supported Living Framework | Carlisle | £185M |
| | Supported Transport Dynamic Purchasing Solution (DPS) | Oxford | £150M |
| | Language Services (Lot 1 - 5) | Liverpool | £148M |
| | Language Services (Lots 1 - 5) | Liverpool | £148M |
| | Ministry of Justice Opportunity-Youth Education Service Provision | London | £132M |
| | YOI Education Service Provision | London | £132M |
| | Reseller Framework - IT Hardware and Software , Software Renewals and Software Asset Management | Reading | £120M |
| | Hyde Group Capital Works Contracts | London | £111M |
| | Field Services (FS) | London | £100M |
| | Outsourced ICT Framework Agreement | Salford | £100M |
| | Property Hard and Soft Facilities Management and Security, Grapevine and Business Support Services | London | £88M |
| | Purchases of 6N Nitrile Examination Gloves | Leeds | £82M |
| | NHS National Pharmaceuticals Transition | Runcorn | £81M |
| | Electrical and Mechanical Building Works | London | £80M |
| | Carlisle Southern Link Road | Carlisle | £75M |
| | Home to School Transport Services - Portsmouth City Council - Dynamic Purchasing System | Hampshire | £75M |
| | BHCC Major Capital Projects | Hove | £70M |
| | West Sussex Electric Vehicle Chargepoint Network | West Sussex | £68M |
| | Energy and Water, Professional Buying Organisation (PBO) or Trading Organisation and Associated Support Services | Taunton | £64M |
| | Property Services - Kitchen and Bathrooms | London | £63M |
| | Minor Works Contractor Framework | Leeds | £60M |
| | Roofing and Associated Works | Livingston | £60M |
| | Community Healthcare Services in Cheshire | Nantwich | £60M |
| | 1) Speech & Language and (2) Dietitian Degree Apprenticeships | Salisbury | £50M |
| | Antivirus and Malware Protection Tool | London | £50M |
| | International Nurse Recruitment Partner, Herts & West Essex ICS | Salisbury | £50M |
| | Planned Maintenance and Minor Works | Stafford | £50M |
| | Lot 3 - Security, Grapevine and Business Support Services | London | £48M |
| | Antivirus and Malware Protection Tool | London | £45M |
| | HS2 Post-Excavation Services | Birmingham | £45M |
| | Frozen Foods | Paisley | £40M |
| | Legal Services Panel | London | £40M |
| | Targeted Tier 2, and Specialist Tier 3, Child and Adolescent Mental Health Services in Buckinghamshire (9qth-Knnl4z)… | Aylesbury | £39M |
| | Settlement Agreement | London | £38M |
| | Municipal Waste Transfer and Treatment | Edmonton | £35M |
| | SBRI for NZIP Energy Storage Programme - Longer Duration Storage Demonstration (Stream 2) | London | £30M |
| | National Framework for Protected Personnel Carriers Including Conversion | Birmingham | £30M |
| | Develop and Construct Appointment of Integrated Supply Team for Holy Trinity College, Cookstown, Co Tyrone -… | Belfast | £29M |
| | Block Contracting Arrangements for Residential With Nursing Care in Furness, Cumbria | Carlisle | £29M |
| | Electrical Equipment, Consumables, Lighting and Cable [3108330] | Ballymena | £27M |
| | Crown Hosting Data Centre Renewal | Manchester | £27M |
| | Property Services - Cyclical Decorations | London | £26M |
| | NEL CCG APMS Procurement - Trowbridge Surgery, Rainham Health Centre and Upminster Medical Centre | London | £26M |
| | National Tutoring Programme Phase 2 | London | £25M |
| | Purchases of Examination Gloves (6N Nitrile, Vinyl, Latex) | Leeds | £25M |
| | Commercial and Industrial Laundry Equipment | Leicester | £25M |
| | Senior Leader & Senior People Professional Apprenticeships | Salisbury | £25M |
| | DUD — Gas Central Heating and Boiler Replacement | Dudley | £24M |
| | Lewisham Homes DLO Repairs Support Contracts | London | £23M |
| | Property Services - Roofing | London | £23M |
| | Diabetic Eye Screening Programmes for Bath and North East Somerset, Swindon and Wiltshire and Dorset | St Austell | £22M |
| | NHS England and NHS Improvement South West (NHSEISW) -Diabetic Eye Screening Programmes for Bath and North… | Bristol | £22M |
| | Supply, Installation, Commissioning and Maintenance of Passive Freight Screening Technology in Northern France & Belgium | Folkestone | £22M |
| | Combined Safety Syringes and Needles for COVID-19 Vaccination Programme - Morbidly Obese Requirement | London | £22M |
| | Civil Parking Enforcement Services (Including Vehicle Removal and TRO Support) | Birmingham | £21M |
| | Property Services - Windows and Doors | London | £21M |
| | Wyken Estate Regeneration (Combined SQ and ) | Coventry | £21M |
| | LOT 1 - Property Hard Facilities Management Services | London | £20M |
| | Communal Doors, Entrance Doors and Associated Products | Livingston | £20M |
| | Roofing and Associated Works | Hengoed | £20M |
| | West Yorkshire Business Accelerator Fund Manager | Leeds | £20M |
| | Property Soft Facilities Management Services | London | £19M |
| | Purchases of Examination Gloves (6N Nitrile, Latex) | Leeds | £17M |
| | Principal Contractor Access Infrastructure and Timber Pond Infill, Pembroke Dock Marine | Pembrokeshire | £17M |
| | Alinity M PCR Reagents | London | £17M |
| | Low Value Construction Services Framework | Sandbach | £16M |
| | Grounds Maintenance and Associated Servcies | Sittingbourne | £16M |
| | Purchases of Examination Gloves (6N Nitrile, Latex) | Leeds | £16M |
| | Flexible Framework for Outdoor Education Centres | Motherwell | £16M |
| | 2 No. Replacement Cremators and Associated Mercury Abatement at Rochdale Crematorium With a 15 Year All… | Sale | £15M |
| | Design and Implementation of Enterprise Technologies - The Essentials Programme | Norwich | £15M |
| | Mechanical and Electrical Works Framework | Nottingham | £15M |
| | Winter Road Surface Treatments 2021 | Northallerton | £15M |
| | Chilled Goods | Edinburgh | £14M |
| | Frozen Food | Edinburgh | £14M |
| | Staffordshire Community Dermatology Assessment and Treatment Service | Stoke on Trent | £13M |
| | North Northamptonshire Council and West Northamptonshire Council - Older Persons' Residential and Nursing Home Services DPS… | Northants | £12M |
| | National Joint Registry: Data Management, Data Solutions and Associated Services | London | £12M |
| | Repair and Overhaul of Various Fire Suppression Repairable Assets and Associated Items | Telford | £12M |
| | Pioneer Group Investment Works Programme | Birmingham | £12M |
| | Disposable Medical Gloves (PPE) for Healthcare Workers for the Care of Patients With Suspected or Confirmed… | London | £10M |
| | Purchases of Examination Gloves (6N Nitrile, Vinyl) | Leeds | £10M |
| | Blended Learning Adult Critical Care Nursing Programme - Health Education England | Leeds | £10M |
| | Communal Doors, Entrance Doors and Associated Products | Hengoed | £10M |
| | CSW WCC - Refresh of the Therapeutic Services Framework for Children Adopted and Placed on a… | Stratford | £10M |