| | Medical Examination Gloves and Surgical Gloves | London | £6B |
| | Euston Station Over Site Development (OSD) — Master Development Partner (MDP) | Birmingham | £4B |
| | NHS for Branded Medicines - National | Runcorn | £2B |
| | Redevelopment of Part of London Liverpool Street Station | London | £2B |
| | Healthcare Clinical Information Systems (HCIS) | Salford | £1B |
| | Rail - Market Engagement Questionnaire Only | London | £1B |
| | Visa and Citizenship Application Services | London | £1B |
| | Visa and Citizenship Application Services (VCAS) | London | £1B |
| | TfL 95052 Bollo Lane Opportunity | London | £1B |
| | Covid-19 Home Testing Fulfilment Services | London | £550M |
| | Residential Care Services (Learning Disability, Physical Disability and Mental Health Needs), Supported Living Services & Care… | Maidstone | £484M |
| | Residential Care Services (Learning Disability, Physical Disability and Mental Health Needs), Supported Living Services & Care… | Maidstone | £476M |
| | Covid-19 Home Testing Fulfilment Services | London | £269M |
| | Evelina Expansion Programme: Main Works | London | £250M |
| | NHSX Market Engagement for GP Cloud Telephony for NHS Organisations | Leeds | £210M |
| | NHS National Pharmaceuticals Transition | Runcorn | £140M |
| | Outpatients Pharmacy | Fareham | £116M |
| | LB Havering Complex Placements Framework - Round 19 | Romford | £100M |
| | Project Aether | Bristol | £100M |
| | Bulk Fuel Supply and Delivery | London | £95M |
| | LD Supported Living - HOWDAB Pt 2 | Oxford | £90M |
| | DMS Support and IBM Software Licences | Telford | £85M |
| | Command Support Air Transport Recapitalisation (CSAT Recap) | Bristol | £80M |
| | Soft Facilities Management Services | Glasgow | £76M |
| | Expanding Pay as You Go on Rail in the South East | London | £68M |
| | Bio Waste Disposal Services | Chelmsford | £60M |
| | Healthy Child Programme in Leicestershire and Rutland | Leicester | £58M |
| | Fostering Agency | Norwich | £50M |
| | NUN - Modern Methods of Construction, Architect and Employer's Agent Framework | Warwickshire | £50M |
| | Precision Machined and Assembled Parts | Telford | £50M |
| | Technology Peripherals and Infrastructure Framework Agreement | Glasgow | £50M |
| | Dermatology Services | Cambridge | £48M |
| | DSA - Platform Services | London | £48M |
| | Dynamic Purchasing System (DPS) for Supported Living and Independent Living (Extra Care Housing) | Norwich | £47M |
| | Swansea University | Swansea | £45M |
| | Harlington School - Main Works | London | £40M |
| | Swindon Adult Community Services | Bath | £40M |
| | Domestic Contact Tracing and Enquiries, Feedback & Complaints Delivery - Lot C | London | £37M |
| | Glossop Fire Station New Build | Ripley | £35M |
| | Procurement of Aircraft | Bristol | £34M |
| | Test and Trace Delivery Partners for Trace, Contain & RTTS Portfolio - Lot A | London | £30M |
| | North Brent School - Main Works | London | £30M |
| | Capital Finance and Option Appraisal Services | Middlewich | £30M |
| | Help to Grow: Digital | London | £30M |
| | Exeter Creative School - Main Works | London | £30M |
| | Deer & Other Wildlife Management Services | Inverness | £27M |
| | Design, Build and Support of Intercept and Escort Craft | Bristol | £26M |
| | Trace, Contain & RTTS Delivery Partner - RTTS Integration Delivery - Lot B | London | £25M |
| | Cambridgeshire County Council Minor Works Framework Covering Building Fabric and Mechanical & Electrical Work | Huntingdon | £24M |
| | Greater Manchester Orthodontic Services | Manchester | £23M |
| | Roche Liat Consumables | London | £22M |
| | National ANPR Service (NAS) PaaS Procurement | Croydon | £21M |
| | Appointment of an IST for New-Bridge Integrated College Loughbrickland | Banbridge | £21M |
| | Assembled Fabricated Parts | Telford | £20M |
| | Brokerage Service | Braintree | £20M |
| | Fabricated Parts | Telford | £20M |
| | Specialist Supported Living Services Framework | Bridgend | £20M |
| | Solar Energy Install | Durham | £20M |
| | Borders & International and Contain CRM Delivery - Lot D | London | £18M |
| | Appointment of an IST for Shimna Integrated College Newcastle | Newcastle | £18M |
| | DWP Voucher Scheme | Northallerton | £18M |
| | National Helpline for NHS Staff | Leeds | £18M |
| | Technical Surveys and Testing - Topographical | Birmingham | £18M |
| | Advanced Mathematics Support Programme Post 16 (AMSP) | London | £17M |
| | Housing Repairs, Maintenance and Voids | Addlestone | £16M |
| | Housing Repairs, Maintenance and Voids Servicing | Addlestone | £16M |
| | Food Waste Treatment Services | Gloucester | £16M |
| | AMML Support | Bristol | £16M |
| | Library Books & Digital Content | Newcastle upon Tyne | £16M |
| | Employee Relocation Services CF | Glasgow | £15M |
| | Roads Materials | Kirkintilloch | £15M |
| | Southern Water Non Infra Framework | Worthing | £15M |
| | Inner Packaging | London | £15M |
| | Data Engineering | London | £12M |
| | Fastershire Community Broadband Grant - Dynamic Purchasing System | Hereford | £12M |
| | Extra Care and Support | Berks | £12M |
| | Littoral Future PDS | Bristol | £12M |
| | Home Office Outbound Postal Services | Liverpool | £11M |
| | BSH / HRA Roofing Framework | Bristol | £11M |
| | HMRC Inland Border Facility Holyhead | Salford | £11M |
| | Cegedim GP System of Choice (GPSoC) | Belfast | £11M |
| | Insurance for Renfrewshire Council and Associated Bodies, and Renfrewshire Valuation Joint Board | Paisley | £10M |
| | Library Books & Digital Content | Newcastle upon Tyne | £10M |
| | Permanent Bridge Beam Infill Shuttering Systems - GRP Forms | Birmingham | £10M |
| | Roofing Framework | Derby | £10M |
| | Cocoa West, York - ENABLING WORKS | London | £9M |
| | Continence Product and Delivery Service | Southampton | £9M |
| | Home Office Outbound Postal Services | Liverpool | £9M |
| | Wiltshire Council | Trowbridge | £9M |
| | Supported Housing Services for Complex Needs | London | £8M |
| | Asset and Lifecycle Management Services | Chester | £8M |
| | Sale of Ground With a Requirement to Enter Into a the Design and Construction of 53… | Dalkeith | £8M |
| | HHC Advanced Manufacturing Centre and Refectory Construction | Rochdale | £8M |
| | CIO Trace Digital and Technology Portfolio Client Side Delivery Partner | London | £8M |
| | External NICS Recruitment | Belfast | £8M |
| | Groundwork Framework | Newcastle upon Tyne | £8M |
| | Highway Capital Improvement Projects Term | Widnes | £8M |
| | Hospital Capacity for Cardiff and Vale Health Board | Cardiff | £8M |
| | Independent Approved Premise - Box Tree Cottage | London | £8M |
| | Maritime/Geospatial Software Support and Development Services - DPS | Taunton | £8M |