| Agilent Technologies Lda | Cheadle, Stockport | 12 | 23 |
| Softcat | Marlow, Wycombe | 12 | 176 |
| Elsevier | None, Tashkent, Noord Holland | 7 | 21 |
| XMA | Nottingham, Wilford | 4 | 93 |
| Biffa Waste Services | High Wycombe, Tyne and Wear | 4 | 36 |
| Shout Digital | Tyne and Wear | 4 | 3 |
| Tesgl | Manchester, Altrincham, Gateshead | 3 | 4 |
| O Communications | Newcastle, Tyne and Wear, Newcastle upon Tyne | 3 | 3 |
| Works Advertising & Design | Chester le Street, County Durham, Durham | 3 | 3 |
| Sideshow | Bournemouth, Dorset | 17 | 17 |
| Jisc Services | North Leigh, Avon | 13 | 24 |
| Idp Connect | Greater London, London | 8 | 8 |
| Illumina Cambridge | Cambridge, Uttlesford | 7 | 20 |
| 10X Genomics | Pleasanton, California | 6 | 7 |
| SMRS | Manchester | 5 | 13 |
| Robertson Construction Group | Stirling | 4 | 11 |
| Mediaworks | Tyne and Wear, Gateshead | 4 | 5 |
| Andrew Charlton | Tyne and Wear | 4 | 4 |
| Wa Communications | Greater London, London | 4 | 4 |
| KPMG | Newcastle upon Tyne, Tyne and Wear | 3 | 102 |
| Penna | London | 3 | 30 |
| Leica Microsystems | Milton Keynes, Breckland | 3 | 16 |
| Fisher Scientific | Loughborough, Leicester | 3 | 14 |
| Harvey Nash | London | 3 | 12 |
| Nikon | Surbiton, Kinston upon Thames | 3 | 5 |
| Ortus Economic Research | Tyne and Wear, Newcastle upon Tyne | 3 | 3 |
| Northern Recruitment Group | Newcastle upon Tyne, Purley | 3 | 3 |
| Horsebridge Network Systems | Cheltenham, Tewkesbury | 3 | 2 |
| Asynt | Isleham | 3 | 3 |
| Attic Consultancy | Northumberland, Longframlington | 3 | 3 |
| Bocm Pauls | Bury St Edmunds, Olympia Mills | 3 | 3 |
| Ivo Associates | Cambridgeshire, Holywell | 3 | 3 |
| Neuteq Europe | Tamworth, West Midlands | 3 | 3 |
| Wardour | London, Greater London | 3 | 3 |
| Whistlejacket London | London, Greater London | 3 | 3 |
| Bytes Software Services | Leatherhead | 2 | 70 |
| Dell Corporation | Bracknell Forest, Bracknell | 2 | 95 |
| Thermo Fisher Scientific | Hemel Hempstead, Halton | 2 | 11 |
| Universal AV Services | Newcastle upon Tyne | 2 | 6 |
| Mathworks | Cambridge | 2 | 5 |
| Philips Healthcare | Guildford | 2 | 7 |
| Oxford University Press | Oxford | 2 | 5 |
| Shiny Sky | Leeds, Leesds | 2 | 2 |
| Admire Taxis | Cramlington, Newcastle upon Tyne | 2 | 2 |
| Feed IT Green | Merseyside | 2 | 2 |
| Opal RT Europe | Sceaux | 2 | 2 |
| Am Technology | Runcorn | 2 | 2 |
| C Gerhardt | Brackley, South Northamptonshire | 2 | 2 |
| Connexin | Hull | 2 | 2 |
| Crunch DMC | Powys, Swansea | 2 | 2 |
| A Dec Dental | Nuneaton, Nuneaton and Bedworth | 2 | 2 |
| Grey Consultants | City of London, Greater London | 2 | 2 |
| Hubspot | Dublin City | 2 | 2 |
| Keyence | Milton Keynes | 2 | 2 |
| Richard Jones | Plymouth | 2 | 2 |
| STCS | Gateshead, Tyne and Wear | 2 | 2 |
| Etek Europe | Monkton | 14 | 14 |
| Dell Computer Corporation | Bracknell | 10 | 13 |
| Inseto | Andover | 9 | 6 |
| Academia | Enfield | 5 | 30 |
| Liveco | County Durham | 5 | 8 |
| Think D | Peterlee | 5 | 5 |
| Bidfood Foodservice | Slough | 4 | 5 |
| Geometric Results | Knutsford | 4 | 10 |
| Pharmaron | Kentucky | 4 | 3 |
| Hays Specialist Recruitment | London | 3 | 80 |
| Stone Computers | Stafford | 3 | 24 |
| Gamma Business Communications | Newbury | 3 | 5 |
| SJ Electronics | Kettering | 3 | 3 |
| Altogether Creative | Tyne and Wear | 3 | 3 |
| Blakell Europlacer | Poole | 3 | 3 |
| Cupio | Basingstoke | 3 | 3 |
| Enigma Interactive | Tyne and Wear | 3 | 3 |
| Newcastlegateshead Initiative | Tyne and Wear | 3 | 3 |
| Shepherd Offshore Group | Newcastle upon Tyne | 3 | 3 |
| Maintel Europe | London | 2 | 13 |
| Gatenby Sanderson | Leeds | 2 | 13 |
| Sellick Partnership | Manchester | 2 | 9 |
| Perrett Laver | London | 2 | 6 |
| Industrial Diagnostics | Merry Lees | 2 | 5 |
| Cytometric Engineering | Ely | 2 | 2 |
| First Face to Face | Gateshead | 2 | 2 |
| Laerdal Medical | London | 2 | 2 |
| Refinitiv | London | 2 | 2 |
| Sprout Social | Chicago | 2 | 2 |
| Vest Construction | County Durham | 2 | 9 |
| NWF Agriculture | Nantwich | 2 | 4 |
| Robertson Construction Nee | Gateshead | 2 | 4 |
| Becton Dickinson CME | Blackpool | 2 | 2 |
| Grahame Gardner | Leicester | 2 | 2 |
| Kone Public | Chertsey | 2 | 2 |
| Konica Minolta Bus Solutions Ukltd | Basildon | 2 | 2 |
| Clear Links Support | Sheffield | 2 | 2 |
| Learning Support Centre | Leicester | 2 | 2 |
| Arraystar | Maryland | 2 | 2 |
| Black & Banton | Gateshead | 2 | 2 |
| Boxmodel Digital Media | Gateshead | 2 | 2 |
| Data Architects | Newcastle | 2 | 2 |
| Ede & Ravenscroft | London | 2 | 2 |
| Elite Sport Performance | Loughborough | 2 | 2 |