| | RFI) Removal and Prevention of Graffiti on the Strategic Road Network | Milton Keynes | £442B |
| | Homecare and Support on the Isle of Wight | Newport | £9B |
| | ICT VAR Framework | Northampton | £5B |
| | Digital and IT Professional Services (DIPS) Framework | Corsham | £1B |
| | Multifunctional Devices, Managed Print and Content Services | Liverpool | £900M |
| | Lifting Equipment & Mobility Aids Framework 2021-A | Birmingham | £800M |
| | Lifting Equipment Mobility Aids Framework 2021-A | Birmingham | £800M |
| | Medical IT | London | £591M |
| | Utilities (Energy Consultancies and LED Lighting Solutions) | Birmingham | £510M |
| | Education Management Systems _ | West Malling | £500M |
| | Foster Care Services | Tonypandy | £440M |
| | Print Management Services | Liverpool | £420M |
| | Adult and CAMHS Mental Health, Learning Disabilities Hospitals | Cardiff | £360M |
| | Independent Schools and Colleges for Children and Young People With Special Educational Needs and Disabilities | Leeds | £360M |
| | Actuarial, Benefits and Governance Consultancy | Norwich | £350M |
| | Vehicles Under Short Term, Flexi and Termed Hire Framework | Widnes | £310M |
| | Asbestos Abatement Framework Procurement 2021-B | Birmingham | £300M |
| | Construction Framework for Pobl Group | Swansea | £265M |
| | Communal Entrance Door Framework | Alfreton | £250M |
| | Passenger Transport | Taunton | £230M |
| | Jobs Growth Wales+ Youth Programme (‘JGW+ Programme’) | Cardiff | £200M |
| | Jobs Growth Wales+ Youth Programme ("JGW+ Programme") | Cardiff | £200M |
| | Access, Quality and Safe Education in Syria (AQSES) | East Kilbride | £160M |
| | Dismounted Joint Fires Integrator (D-Jfi) | Bristol | £150M |
| | IT Products Services (Ii) Lot 2b | Cardiff | £150M |
| | The Galleries Redevelopment Project | Wigan | £130M |
| | DoF Land and Property Services Landweb Extension | Belfast | £125M |
| | Subject Knowledge Enhancement (SKE) | London | £122M |
| | Subject Knowledge Enhancement (SKE) Training Courses | London | £122M |
| | Waste Collection Services on Behalf of Stratford and Warwick District Councils | Leamington Spa | £120M |
| | FTS-FOI-YOI Education Service Provision | London | £109M |
| | Watford Community Housing Flexible Fleet Framework | Watford | £100M |
| | Negative Pressure Wound Therapy | London | £98M |
| | Forum, King's Quarter, Gloucester | Gloucester | £94M |
| | Demolition Framework | London | £80M |
| | TETRA Based Device to Device Remote Speaker Microphone (RSM) for Use With LTE Handheld Mobile Devices… | London | £80M |
| | Energy Efficiency Retrofit Projects - Managing Agent | Ely | £78M |
| | Office Furniture Solutions and Associated Services | Wakefield | £75M |
| | HS1 Private Wire Power Purchase Agreement | London | £70M |
| | Metered Electricity | Belfast | £67M |
| | Herpes Zoster (Shingles) Vaccine(recombinant, Adjuvanted) | London | £66M |
| | Radioactive Metallic Waste Treatment Services Framework | Seascale | £65M |
| | Covid-19 Consumables | London | £65M |
| | End-To-End Serology Testing Service for COVID-19 Testing | London | £62M |
| | Appliances and Electricals Framework | London | £60M |
| | Highway Related Services | Sale | £60M |
| | DfE - Skills for Life and Work Programme | Belfast | £60M |
| | Surge (With Variations 1-4) | London | £59M |
| | West Yorkshire Out of Hours Primary Medical Services | Huddersfield | £57M |
| | Single Non-Emergency Number (SNEN) | Croydon | £55M |
| | Integrated Healthcare in Police Custody and Liaison and Diversion in Police Custody and GM Criminal Courts… | Manchester | £52M |
| | Command and Staff Academic Provision | Swindon | £50M |
| | General Machined and Fabricated Parts for Military Vehicles | Telford | £50M |
| | London and Quadrant Housing Trust - Supply and Fix Kitchen Units Framework 2021 - 2025 | London | £50M |
| | North Devon Link Road | Exeter | £47M |
| | Courier Services for Patient at Home and Outreach Services | Manchester | £46M |
| | Food to Go | London | £42M |
| | Testing Requirements Related to Covid-19 | London | £42M |
| | Tubes and Funnels for Covid-19 Testing | London | £40M |
| | Multi-Functional Devices and Document Solutiuons | Cardiff | £40M |
| | Solar Framework | Truro | £40M |
| | Laboratory Testing Services | London | £38M |
| | Kirklees Integrated Sexual Health Service | Huddersfield | £37M |
| | University of Sunderland — Minor Works (Main Contractors Framework) | Sunderland | £36M |
| | Waste Management Equipment Support | Bristol | £35M |
| | Waverley Borough Council Repairs, Aids and Adaptations, Void Refurbishment | Godalming | £32M |
| | Laboratory Information Management System | Preston | £30M |
| | NE Lifts Consultancy, Maintenance, Refurbishment and Associated Installation Services Agreement | Leeds | £30M |
| | Office Supplies | Newcastle upon Tyne | £30M |
| | PPE for the Emergency Services and Wider Public Sector | Wakefield | £30M |
| | Workforce Management System | Bicester | £30M |
| | LLWR ESC Support Framework | Calderbridge | £28M |
| | Castle Mills | York | £27M |
| | Passenger Transport Services | London | £27M |
| | Interpretation and Translation Services | Salford | £25M |
| | Planning Consultant Services | London | £25M |
| | Project Construction Professional Services Framework Agreement | Leicester | £25M |
| | SCC DW Surrey Children’s Emotional Wellbeing and Mental Health Service (EWMH) | Kingston upon Thames | £24M |
| | Design and Application of Carriageway Surface Dressing 2021 | Exeter | £24M |
| | Surgical Type IIR Masks | Cardiff | £23M |
| | Appointment of Integrated Supply Team for the New Ardnashee School and College Co. Derry, Ref: MA14… | Belfast | £23M |
| | Communal Mechanical Plant (Servicing, Planned Preventative Maintenance and Repair) | London | £23M |
| | Innovation - Samba COVID19 Testing Equipment and Consumables Innovation - Samba COVID19 Testing Equipment and Consumables… | London | £20M |
| | Accessible Oldham Strategic Partnership | Oldham | £20M |
| | Air Scida ( Sites Site Coordination Installation Design Authority) | High Wycombe | £20M |
| | EOECPH DPS for Specialist Pharmacy Courier Services for Deliveries to Patients | Fulbourn | £20M |
| | Integrated Theatres Related Products and Services | London | £20M |
| | 16+ Semi-Independent Living Supported Accommodation Service | Enfield | £20M |
| | Uniforms - BF/IE, UKVI/HMPO, MoE Clothing/Equipment | London | £19M |
| | Mandatory Dental Services (MDS) in Kent, Surrey and Sussex to NHS England and NHS Improvement (South… | Kent | £19M |
| | RBK Greenspace Services | Kingston upon Thames | £18M |
| | Dynamic Purchasing System for Building Safety and Security Systems | London | £18M |
| | FoOM Tools and Systems | Exeter | £18M |
| | Future of Operational Meteorology (FoOM) Tools and Systems | Exeter | £18M |
| | Type IIR Surgical Masks | Cardiff | £18M |
| | Cleaning and Caretaking Services for Schools and Corporate Properties | Gloucester | £17M |
| | CHC Fast Track Bed Framework and Immediate Block Purchase Bed Requirement | Eastleigh | £17M |
| | Community Based Wellbeing Services: Lots 1, 2 and 3 | Maidstone | £16M |
| | Adult Male and Female; Acute, PICU and Rehabilitation Inpatient Bed | Birmingham | £16M |
| | GP Out of Hours Service in East Berkshire | Windsor | £16M |