| | Healthcare Services by NHS and Other Public Bodies (Including Clinical Services) | Sheffield | £2B |
| | Decontamination Services and Solutions | Hemel Hempstead | £2B |
| | Residential and Nursing Care Home Services | Lewes | £2B |
| | Patient Transport Services | Hemel Hempstead | £1B |
| | Electricity (Half Hourly Metered, Non-Half Hourly and Unmetered Supply) | Leicester | £960M |
| | Asset Decarbonisation and Retrofit Dynamic Purchasing System (E,W,NI) | Warrington | £950M |
| | Asset Decarbonisation and Retrofit Dynamic Purchasing System (E,W&NI) | Warrington | £950M |
| | Publication of Redacted | Sheffield | £873M |
| | Energy to Catholic Education Establishments in England & Wales | Cannock | £800M |
| | Insourcing of Clinical Services | Hemel Hempstead | £800M |
| | Publication of Redacted | Sheffield | £706M |
| | A2Dominion Housing Maintenance Joint Venture for the London Region | London | £575M |
| | Publication of Redacted | Sheffield | £558M |
| | Property Construction Partnership Framework | Maidstone | £500M |
| | Sustainable Healthcare Waste Management: Minimisation, Repurposing & Recycling Services | Hemel Hempstead | £500M |
| | NHS National Generic Pharmaceuticals Wave 13 | Runcorn | £470M |
| | NHS SBS Sustainable Transport for Healthcare Services Dynamic Purchasing System (DPS) | Hemel Hempstead | £300M |
| | Residential and Nursing Care Home Services | Stafford | £275M |
| | NHS National Pharmaceuticals Transition | Leeds | £268M |
| | Bleeding Disorders Including Haemophilia B | Runcorn | £250M |
| | Digital Dictation, Speech/Voice Recognition, Outsourced Transcription and Associated Services | Leatherhead | £200M |
| | Legal Services for Health | Hemel Hempstead | £200M |
| | Cambridgeshire County Council Early Years Pseudo DPS | Huntingdon | £186M |
| | Rick Roberts Way Developer Partner Procurement | London | £165M |
| | Temporary and Permanent Staffing | Salford | £160M |
| | CCTV, Security Equipment and Services Framework | Doncaster | £150M |
| | Waste Transfer Stations and the Disposal of Waste | Matlock | £146M |
| | WAV PT Waverley Borough Council Leisure Operating | Godalming | £145M |
| | Local Bus Services and School Bus Servics in Lancashire | Preston | £140M |
| | Future Protected Modem Type-A (FPM-A) | Corsham | £120M |
| | Successful Bidder to Procure Further Sub-Categories of Microbiology | Southampton | £118M |
| | Highways Term Maintenance Contracts - Halton Borough Council and Warrington Borough Council | Widnes | £117M |
| | Essex Integrated Sexual Health Service | Chelmsford | £109M |
| | NHS Prescriptions, Print and Cards Framework Pre-Tender Market Engagement (PTME) and (RFI) | Newcastle upon Tyne | £100M |
| | Community Diagnostics Services in North East London | London | £97M |
| | Supported Living Services for Individuals With a Learning Disability, Autistic Spectrum Conditions and/or Mental Health Conditions… | Stafford | £94M |
| | All Age Transport Dynamic Purchasing System | Ealing | £90M |
| | Design and Construction of Immingham Eastern RORO Terminal and Marine Infrastructure | Hull | £90M |
| | CAR - Emergency Accommodation Open Framework | Bristol | £80M |
| | Joint Venture for Development of Multiple Sites in Suffolk | Ipswich | £75M |
| | Parking Management Solutions | Leicester | £75M |
| | Hereditary Angioedema | Runcorn | £74M |
| | CCTV, Security Equipment and Services Framework | Doncaster | £70M |
| | ETE079 - Provision of Household Waste Recycling Centre Management Services and the Supply of Goods | Matlock | £70M |
| | Essex Integrated Sexual Health Service | Chelmsford | £65M |
| | Alcohol and Drug Treatment and Recover Services | Bradford | £64M |
| | Leisure Services | Shrewsbury | £62M |
| | Somalia Stability Fund III (SSF III) | London | £60M |
| | NHS National Pharmaceuticals Transition | Runcorn | £59M |
| | Associate Continuing Healthcare Practitioner Apprenticeship | Salisbury | £50M |
| | Grocery Provisions, Frozen & Chilled Foods | Nottinghamshire | £48M |
| | Repair, Refurbishment and Modernisation Works at Properties Owned or Managed by Grand Union Housing Group at… | Buckinghamshire | £47M |
| | Covid 19 and Related Programmes | Leeds | £45M |
| | Integrated Sexual and Reproductive Health Services | Bradford | £43M |
| | Leisure Services to the Vale of Glamorgan Council | Barry | £41M |
| | WHSCT Framework for Building Maintenance and Building Minor Works (TSSC) | Belfast | £40M |
| | Expert Advisory Call Down Service 2 (EACDS 2) | East Kilbride | £39M |
| | Independent Living Products | Hertford | £36M |
| | Step Down Beds Framework - NHS Bedfordshire, Luton and Milton Keynes ICB | Luton | £36M |
| | Agora Redevelopment Scheme | Milton Keynes | £33M |
| | Agreements for the Start-Up Loans Company's Business Support Partner Services | Sheffield | £32M |
| | Agreements for the Start-Up Loans Company’s Business Support Partner Services | Sheffield | £32M |
| | National Careers Service - Community Based Service - West Midlands | London | £32M |
| | NHS Education With Northampton General Hospital NHS Trust | Leeds | £31M |
| | NHS Education With Northampton General Hospital NHS Trust | Leeds | £31M |
| | GM Collaboration - HR/Payroll System GMCA 400 | Salford | £31M |
| | Discretionary Assistance Fund Framework Agreement | Cardiff | £30M |
| | Royal Navy Shared Service Centre | Portsmouth | £30M |
| | NHS Education With Chesterfield Royal Hospital NHS Foundation Trust | Leeds | £29M |
| | NHS Education With Chesterfield Royal Hospital NHS Foundation Trust | Leeds | £29M |
| | Building Fabric Maintenance and Minor Works Framework Agreement | Leicester | £28M |
| | Taxi Service for Vulnerable Clients | Bradford | £28M |
| | National Careers Service - Community Based Service - London | London | £28M |
| | NHS Education With Kettering General Hospital NHS Foundation Trust | Leeds | £26M |
| | NHS Education With Kettering General Hospital NHS Foundation Trust | Leeds | £26M |
| | National Careers Service - Community Based Service - North West | London | £25M |
| | Community Based Day Opportunities Q4 01 April 2022 to 30 June | Stafford | £25M |
| | Data Services Alliance Access - Change | Leeds | £25M |
| | EPOS Deployment and Migration | London | £25M |
| | Services Concession the Operation of Northumberland Energy Park Dock | Ashington | £25M |
| | NHSE/I Microsoft LSP & CSP Partner | Leeds | £24M |
| | Personal Protective Equipment (PPE) Including Pandemic Recovery Items & Workwear | Paisley | £24M |
| | National Careers Service - Community Based Service - Yorkshire & the Humber | London | £23M |
| | S From SPT's Dynamic Purchasing System (DPS) 01/04/2022 - 30/06/ | Glasgow | £22M |
| | Personalised Assessments in Reading and Numeracy | Cardiff | £21M |
| | NHS Education With Coventry and Warwickshire Partnership NHS Trust | Leeds | £20M |
| | NHS Education With Coventry and Warwickshire Partnership NHS Trust | Leeds | £20M |
| | Childrens Home Services | Preston | £20M |
| | Rail Replacement | London | £20M |
| | Delivering Better Value In | Manchester | £19M |
| | National Careers Service - Community Based Service - South East | London | £19M |
| | CCUS Development - Legal Advisory Support | London | £18M |
| | HIS Repairs, Maintenance and Voids | Bridgwater | £18M |
| | National Careers Service - Community Based Service - South West | London | £17M |
| | Adult Influenza Vaccines - Secondary Care | Runcorn | £16M |
| | Mechanical and Electrical Engineering Framework | Nottingham | £16M |
| | Incentivising Green Infrastructure Public Access and Biodiversity Creation in Land Management | London | £16M |
| | DOJ PSNI Managed Service Requirement ANPR | Belfast | £15M |
| | National Careers Service - Community Based Service - North East | London | £15M |
| | LiveWest - Design and Build 79 Homes at Foxes Field, Gulval, Cornwall | Exeter | £15M |