UKRI-1161 Laser Micro-dissection Inverted Imaging System

Concepts

• swindon
• precision equipment
• ukri-1161 laser micro-dissection
• supply of mmi laser microdissection
• attached laser
• system
• addition of a confocal microscope
• laboratory and optical equipment
• fluorescence microscope
• tissue

Location

United Kingdom: UNITED KINGDOM

Description

Supply of MMI Laser Microdissection Inverted Imaging System with the ability to measure the presence of the oligonucleotide-based drugs (i.e. antisense and siRNA) within the tissue and assess drug action through measurement of changes in the mRNA and protein levels of the drug target. We require a brightfield/fluorescence microscope that can be employed to view, record and quantify tissues stained by H&E, in situ hybrisation (ISH) and immunohistochemistry (IHC). We also require an attached laser that can be employed to provide tissue section down to the single cell level for the analysis of drug, mRNA and protein levels. In addition, we require a system that can be expanded in the future through the addition of a confocal microscope.

Award Detail

Award Criteria

CPV Codes

• 38000000 - Laboratory, optical and precision equipments (excl. glasses)

Legal Justification

This system was chosen as it needed to integrate into current systems and equipment on site and was therefore the only option. Only the Olympus MMI Laser Microdissection Inverted Imaging System has a modular system which allows the addition, integration and onboarding of these facilities such as confocal microscopy, live cell imaging and high content screening to provide a system that can deliver all of the following functions: live cell imaging, spinning disc confocal and high content screening, whilst retaining the original functionality of the system and without hardware replacement. Also, we require a laser to micro-dissect single cells and tissue biopsies for quantifiable analysis such as RT-PCR, sequencing and western blotting. The sample capture procedure must be an upward capture system in order to reduce contamination of samples to a minimum. It must be possible to maintain an RNA-ase and DNA-ase free environment. This is the only equipment able to deliver all the above as an integrated system.

Other Information

** PREVIEW NOTICE, please check Find a Tender for full details. ** To view this notice, please click here: https://www.delta-esourcing.com/delta/viewNotice.html?noticeId=569061891 GO Reference: GO-2021220-PRO-17818495