11C]PBR28 PET and MRI scanning, radioligand production, LPS (lipopolysaccharid) supply and biomarker analysis

Concepts

• medical imaging
• exeter
• hammersmith hospital campus
• uk provider of pet tracers
• radioligand production
• radioligand development platform
• pet
• scans
• mri
• lps

Location

South West England:

Description

PET and MRI scanning, radioligand production, LPS (lipopolysaccharid) supply and biomarker analysis

Total Quantity or Scope

• Only UK provider of PET tracers [11C]BU90008, [11C]SA4503, and [18F]BCPP-EF, that are currently used for our studies. • Invicro is located within the Hammersmith Hospital Campus, its location accommodates research participants for image and clinical assessments without increased burden and travel for the participants. While also reducing cost and time to conduct the studies. • [11C] tracers (with short half-life of about 20 minutes) and of [18F] radiotracers (with half-life of about 120 minutes) are produced in house and the short half-life of the [11C] tracers means Invicro’s two in-house cyclotron’s must be used. Their radioligand development platform means implementation of new tracers is not available at other facilities. • Invicro has the equipment and facilities to collect arterial blood samples during the scans and analyze the quantity of the radioactive metabolites on site.

Award Detail

CPV Codes

• 85150000 - Medical imaging services
• 73111000 - Research laboratory services

Legal Justification

PET and MRI scanning, radioligand production, LPS (lipopolysaccharid) supply and biomarker analysis • Only UK provider of PET tracers [11C]BU90008, [11C]SA4503, and [18F]BCPP-EF, that are currently used for our studies. • Invicro is located within the Hammersmith Hospital Campus, its location accommodates research participants for image and clinical assessments without increased burden and travel for the participants. While also reducing cost and time to conduct the studies. • [11C] tracers (with short half-life of about 20 minutes) and of [18F] radiotracers (with half-life of about 120 minutes) are produced in house and the short half-life of the [11C] tracers means Invicro’s two in-house cyclotron’s must be used. Their radioligand development platform means implementation of new tracers is not available at other facilities. • Invicro has the equipment and facilities to collect arterial blood samples during the scans and analyze the quantity of the radioactive metabolites on site.

Other Information

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