UKRI-1682 Mass Photometer

Concepts

• ukri-1682 mass photometer
• swindon
• instruments
• sec
• molecular mass
• supply of mass photometer
• mass photometry
• different mass
• mass of each molecule
• measurement of the hydrodynamic radius

Location

UNITED KINGDOM

Description

Supply of Mass photometer and maintenance service: It derives molecular mass not indirectly from a measurement of the hydrodynamic radius (e.g. SEC or DLS) but from light scattered by single molecules, making it uniquely suited to differentiate between particles of similar size but different mass (e.g. loaded vs. unloaded gene delivery particles). As mass photometry measures the mass of each molecule individually it is uniquely suited to inform about complex samples and processes including sub-populations lost in ensemble measurements (e.g. SPR, BLI or DLS). The measurements can be done directly in solution, on minimal sample amounts and in a variety of buffer conditions.

Award Detail

Award Criteria

CPV Codes

• 38400000 - Instruments for checking physical characteristics
• 38424000 - Measuring and control equipment

Indicators

• Award on basis of price.

Legal Justification

Mass photometry provides truly unique benefits as it derives molecular mass not indirectly from a measurement of the hydrodynamic radius (e.g. SEC or DLS) but from light scattered by single molecules, making it uniquely suited to differentiate between particles of similar size but different mass (e.g. loaded vs. unloaded gene delivery particles). As mass photometry measures the mass of each molecule individually it is uniquely suited to inform about complex samples and processes including sub-populations lost in ensemble measurements (e.g. SPR, BLI or DLS). The measurements can be done directly in solution, on minimal sample amounts and in a variety of buffer conditions. Refeyn TwoMP mass photometer is currently the only commercial system available providing single-molecule scattering contrast of sufficient quality, reproducibility and stability to allow for direct correlation to molecule mass. It achieves this by building on a portfolio of Intellectual Property Rights licensed exclusively to or developed by Refeyn Ltd (e.g. US10775597B2 / EP3485309B1 / JP2019520612 / CN109477955, US10816784B1, DE202019100833 / CN20987913/ JP3222366, WO2019110977, GB2588378, WO2020052522).

Other Information

To view this notice, please click here: https://ukri.delta-esourcing.com/delta/viewNotice.html?noticeId=639369772 GO Reference: GO-2021111-PRO-19166793