Use of PET and MRI imaging facilities, plus [11C] radiopharmaceuticals at Invicro LLC

A Contract Award Notice
by UNIVERSITY OF EXETER

Source: Find a Tender
Type: Contract (Goods)
Duration: not specified
Value: £2M

Sector: HEALTH
Published: 21 Oct 2022
Delivery: not specified
Deadline: n/a

Concepts

Location

Devon:

Geochart for 1 buyers and 1 suppliers

1 buyer

Exeter University Exeter

1 supplier

Imanova Invicro Llc

Description

PET and MRI scanning, radioligand production, and biomarker analysis

Total Quantity or Scope

• Only UK provider of PET tracers [11C]BU90008, [11C]SA4503, and [18F]BCPP-EF, that are currently used for our studies. • Invicro is located within the Hammersmith Hospital Campus, its location accommodates research participants for image and clinical assessments without increased burden and travel for the participants. While also reducing cost and time to conduct the studies. • [11C] tracers (with short half-life of about 20 minutes) and of [18F] radiotracers (with half-life of about 120 minutes) are produced in house and the short half-life of the [11C] tracers means Invicro’s two in-house cyclotron’s must be used. Their radioligand development platform means implementation of new tracers is not available at other facilities. • Invicro has the equipment and facilities to collect arterial blood samples during the scans and analyze the quantity of the radioactive metabolites on site.

Award Detail

1	Imanova (Invicro Llc) TBC Reference: 029714-2022-1 Value: £1,883,380

Award Criteria

price

CPV Codes

33692000 - Medical solutions

Legal Justification

The research conducted by the Neurodegeneration Imaging Group requires the use of [11C] radiopharmaceutical, as well as an imaging facility that can provide PET-MR scanners with accompanying arterial line capabilities. Due to the very short half-life of the the [11C] tracers, these research studies are limited to facilities that have an in-house cyclotron. Imanova, trading as Invicro, not only has the in-house production of the [11C] tracers, which have a short half-life of approximately 20 minutes and the [18F] radiotracers with a half-life of approximately 120 minutes, they also host two cyclotrons on site. This coupled with the research facility’s location in London, where participants who are participating in the study have clinics has resulted in, for technical reasons, only Invicro being able to provide the tracers and in-house service to deliver the research outputs at present.