The Supply, Delivery and Maintenance of a Illumina NextSeq 1000 Sequencing System and Associated Consumables

Concepts

• associated consumables
• maintenance of a illumina nextseq
• cheshire
• precision equipment
• maintenance of a illumina nextseq
• integrated system
• consumables
• illumina nextseq
• system
• laboratory and optical equipment

Location

Cheshire East:

Description

The Supply, Delivery and Maintenance of a Illumina NextSeq 1000 Sequencing System and Associated Consumables.

Total Quantity or Scope

The Supply, Delivery and Maintenance of a Illumina NextSeq 1000 Sequencing System and Associated Consumables to the Medicines Discovery Catapult Ltd. The Illumina NextSeq 1000 Sequencing System is an integrated system for automated generation of DNA clonal clusters by bridge amplification, sequencing, primary analysis, and secondary analysis. The system includes embedded touchscreen monitor and on-instrument computer, control software, hardware accelerated analysis pipelines. The contract includes delivery, installation, maintenance and training. The associated consumables are also included in the scope of this contract.

Award Detail

CPV Codes

• 38000000 - Laboratory, optical and precision equipments (excl. glasses)

Legal Justification

The Illumina sequencer for GeoMx is required by the Medicines Discovery Catapult Ltd (MDC) as it forms part of the GeoMx workflow for whole spatial transcriptome analysis. Illumina sequencer for GeoMx is required, there is no competition and competition is absent for technical reasons as the Illumina sequencer for GeoMx is the only instrument which has access to Illumina adapters within the nanostring reagents. Nanostring have developed a workflow with Illumina where Illumina’s i5 and i7 sequences specifically add P5 and P7 sequences for binding to Illumina’s flow cell. These sequences are part of the SeqCode that are for the library prep and there are no alternative sequences to obtain for analysis. Furthermore, the software offers a selection of Illumina sequencers to choose from when finalizing the readout group (to be able to start sequencing) – this will create files that are tailored towards use on the respective Illumina platforms. Most of all, the sequences (FASTQ files) need to be processed in order to be made compatible with the GeoMx for import. The pipeline software is tailored to work with the Illumina output files (including Illumina’s index sequences) and cannot be used on sequences produced by any other system. Or you can directly process these files within Illumina’s BaseSpace environment. The purchase of the equipment will enable a fully integrated workflow of the two systems. The MDC will follow a 10 day standstill period ending on midnight on Friday 26th November 2021. Following the successful completion of the standstill period the MDC will award the contract to Illumina Cambridge Ltd.

Other Information

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