Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

Concepts

• research services
• dundee
• other chemistry services outsourcing framework
• chemistry services outsourcing framework
• other chemistry services outsourcing
• chemistry synthesis
• chemistry services
• term framework
• none chemistry synthesis
• the provision of chemistry synthesis

Location

Biological Chemistry & Drug Discovery (BCDD), University of Dundee

Description

This Second-Generation Framework is required to provide a quick route to market for the provision of Chemistry Synthesis and other Chemistry Services. The initial contract term will be two (2) years, with the option to extend for 2 x 12 months, if required, at the sole discretion of BCDD and subject to ongoing satisfactory performance by the appointed Service Providers The Chemistry Synthesis and Other Chemistry Services required will include: 1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important; 2. Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale; -Scale up of chemistry, up to 200g; -Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale. -Synthesis of intermediates at 5-100g; For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%; -Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes. The subsequent route to market will be via Mini Comp under the Framework.

Ammendments to Previous Notice

Award Detail

CPV Codes

• 73110000 - Research services

Indicators

• Contract modified due to additional needs.

Legal Justification

As per above

Other Information

(SC Ref:784551)