| | Lateral Flow - Dynamic Purchasing System (DPS) | London | £8B |
| | Lateral Flow Dynamic Purchasing System Process Webinar | London | £8B |
| | Interventional Cardiology, Radiology and Neuroradiology, Cardiac Rhythm Management and Electrophysiology (CRM and EP) | London | £3B |
| | Strategic Property Development Partner | Warwick | £2B |
| | Secondary Care Access and Discharge Services | Sheffield | £1B |
| | Merchants Framework 2021 | Alfreton | £1B |
| | Manufacture of Lateral Flow Antigen Tests for Sars-Covid-2 | London | £1B |
| | Low Carbon Offsite Construction DPS | Uxbridge | £1B |
| | Workplace and Facilities Framework | Prescot | £1B |
| | Lateral Flow Testing Kits | London | £912M |
| | Electricity and Natural Gas | Belfast | £600M |
| | Energy Efficient Retrofit Installers Dynamic Purchasing System | Nottingham | £500M |
| | Heating and Hot Water Systems Framework | Derbyshire | £500M |
| | Multi-Disciplinary Consultancy Services (MDC1) - CPC and London & SE | Uxbridge | £500M |
| | Supplier Day for New Decommissioning & Asbestos Removal (DAR) Framework | Thornbury | £485M |
| | Summer Boiler Works | Canterbury | £400M |
| | DHSC/Medicom20200619 | London | £308M |
| | Employee Benefits for Health, Wealth and Wellbeing Framework | Sheffield | £300M |
| | Endoscopy Consumables and Associated Products | London | £300M |
| | Neutral Vendor Provider — Open | Ealing | £300M |
| | Neutral Vendor Provider -OPEN | Ealing | £300M |
| | Refuse and Associated Specialist Electric Vehicles Dynamic Purchasing System | Hampshire | £260M |
| | Door Entry, Access Control System and CCTV Systems Framework | Derbyshire | £250M |
| | Logistics Support | Bristol | £250M |
| | Workplace and Facilities Framework | Prescot | £250M |
| | Veterinary Delivery Partnership - Livestock Testing Services in England and Wales | London | £205M |
| | Global Evaluation Framework | East Kilbride | £200M |
| | Highway Maintenance, Design, Construction and Other Services - CPU 455 | Oxford | £166M |
| | Orthotic Services and Associated Consumables | Normanton | £160M |
| | Minor Works Framework 2021 | Hampshire | £130M |
| | Payment Gateway and Merchant Acquirer Services | Swansea | £123M |
| | Deloitte NTP Phase 5 | London | £123M |
| | Endourology Products and Accessories | London | £120M |
| | TfL 93871 RideLondon | London | £112M |
| | ARP Field Services | London | £100M |
| | Community Accommodation Service Tier-2 (Formally Named Bail Accommodation and Support Service) | London | £100M |
| | Community Accommodation Service - Tier 2 (Formerly Named Bail Accommodation and Support Service) | Westminster | £100M |
| | Objective Structured Clinical Examination (OSCE) Delivery Services | London | £100M |
| | Supply, Installation and Maintenance of Low Carbon Electrical Micro-Generation Technologies | Wakefield | £100M |
| | Workplace Supply Solutions | Birmingham | £100M |
| | Specialist Personal Protective Equipment (PPE) | Maidstone | £98M |
| | ARMOUR Centre Support | Warminster | £90M |
| | ARMOUR Centre Support (Project ARGONAUT) | Warminster | £90M |
| | Green Homes Grant Voucher Scheme Administration | London | £88M |
| | One HMG Movement of Personal Effects | London | £88M |
| | Electronic Human Resource and Related ICT Services Northern Ireland Civil Service (E-HR Programme) | Belfast | £87M |
| | Oncology Ablation Devices, Consumables and Associated Equipment | London | £85M |
| | Q-PCR Lab Consumables Supply for LHL | London | £85M |
| | Domiciliary Support Service 2020 Lot 1 - General Domiciliary Support in Leicester City | Leicester | £83M |
| | Urology, Bowel and Faecal Management | Normanton | £83M |
| | Framework for Frozen Food and Groceries | London | £80M |
| | Frozen Foods and Groceries | London | £80M |
| | Project_25787 - Decarbonisation Programme - Project_25787 - Decarbonisation Programme - Project CoPPA | London | £80M |
| | Technology and Management Agent - Food Supply and Delivery Platform | Liverpool | £75M |
| | Vascular Therapy and Associated Products | Normanton | £72M |
| | Feltham and Surrey Prisons | London | £69M |
| | Metered Electricity | Belfast | £67M |
| | Market Engagement - Building Safety Improvements - The Guinness Partnership | London | £63M |
| | Electrical Consumables and Associated Items | Telford | £60M |
| | Expert Advisory Call Down Services | East Kilbride | £60M |
| | External Placements for Looked After Children - Re-Opening | Grays | £60M |
| | Light & Heavy Protected Mobility Vehicle Spares | Telford | £60M |
| | Workforce Transformation Solutions | Chester | £60M |
| | New Enterprise Allowance Phase 2 | Leeds | £56M |
| | Grounds Maintenance and Tree Services | London | £55M |
| | Natural Gas | Belfast | £54M |
| | Energy Efficient Retrofit Professional Services | Nottingham | £50M |
| | Light & Heavy Protected Mobility Vehicle Spares | Telford | £50M |
| | Office Supplies Call Off | Liverpool | £48M |
| | Treatment of Organic Waste Services | Paisley | £48M |
| | Traffic Scotland Systems (TSSC) | Glasgow | £47M |
| | Buckinghamshire Integrated Community Equipment Service | Aylesbury | £44M |
| | Flat Roof Replacement & Parapet Repairs at Clacton Police Station | Essex | £43M |
| | Community Drug and Alcohol Prevention, Treatment and Recovery Service | Leeds | £43M |
| | Maternity Obstetrics and Gynaecological Products | Normanton | £40M |
| | Northumberland Line Stations Construction Project | Morpeth | £40M |
| | Passive Fire Remedial Works | Croydon | £40M |
| | Wheeled Bins | Wakefield | £40M |
| | Highways England Winter Fleet Replacement (2021 | Birmingham | £38M |
| | Infant Feeding and Associated Accessories | Normanton | £32M |
| | Supported Living Services | Bridgend | £32M |
| | Adult Skills Training Framework | West Yorkshire | £30M |
| | Direct Payment Support Services Framework | Nottingham | £30M |
| | OLE Wire Framework - Request for Supply Chain Input Into Strategy | London | £30M |
| | Daily Living Aids Including Walking Aids | Normanton | £29M |
| | Repair of Various Line Replacement Units (LRU's) and Associated Items | Telford | £28M |
| | Training in Education Leadership and Strategic Management Skills — DPS for Skills Providers and Training Provision,… | Chester | £27M |
| | Hades 2020 | Croydon | £27M |
| | Medical Pulp August | Sheffield | £26M |
| | Inhalation Anaesthetics and Vaporisers | Runcorn | £26M |
| | NHS National Generic Pharmaceuticals - Inhalation Anaesthetics and Vaporisers | Runcorn | £26M |
| | Services to Recruit International Foundation Students for the University of Birmingham | Birmingham | £25M |
| | Surrey and Sussex Bluelight Accident Repair | East Sussex | £25M |
| | Waste and Recycling Collection and Street Cleansing Services and Processing of Dry Recycling | Rochford | £25M |
| | Endoscopy Services to Oxfordshire Clinical Commissioning Group | Oxford | £25M |
| | Breakfast Clubs Programme | London | £24M |
| | Standard Length Examination Gloves, Nitrile | Belfast | £21M |
| | IRM20/7530 - The Supply of Tyres | Telford | £21M |
| | Testing of Electrical Installations and Remedial Works Boroughwide | London | £21M |
| | Design and Construct New Dunclug College, Ballymena - Ref MA16-000D14 | Belfast | £20M |