| | NHS England Increasing Capacity - Refresh | Leeds | £10B |
| | Southern Construction Framework 5 (SCF 5) | Winchester | £4B |
| | Southern Construction Framework 5 (SCF-5) | Hampshire | £4B |
| | ACCESS Pool Investment Manager for Real Estate - UK Core | Hampshire | £2B |
| | OSHA MMC Cat 1 & Cat 2 Framework | Manchester | £2B |
| | Future NHS Workforce Solution (Including Electronic Staff Record (ESR) Services) | Newcastle upon Tyne | £2B |
| | NHS SBS Healthcare Planning, Construction Consultancy and Ancillary Services (HPCCAS) | Hemel Hempstead | £2B |
| | NHS National Proprietary Pharmaceuticals | Runcorn | £2B |
| | Corporate Power Purchase Agreement CPPA2 | London | £1B |
| | Gigabit Infrastructure Subsidy Programme - Cross-Regional Framework (Type C) | London | £800M |
| | IT Reseller Framework | Derbyshire | £600M |
| | Modern Methods of Construction (MMC) New Homes Framework NH3 | Uxbridge | £600M |
| | Stratford Waterfront and Bridgewater Residential Joint Venture Development Partner | London | £600M |
| | Conflict, Stability & Security Fund (CSSF) Framework Re-Tender 2018 - Extension and Value Uplift | London | £500M |
| | Construction and Trades Sub Contractor Framework | Glasgow | £500M |
| | Devlopers to Provide Land, Design & Build Solutions for Social Housing | Belfast | £500M |
| | Merseytravel Bus Services DPS | Liverpool | £500M |
| | Modern Methods of Construction (MMC) New Homes Framework NH3 | Livingston | £500M |
| | Passenger Transport - Dynamic Purchasing System | Trowbridge | £500M |
| | NHS London Branded Medicines - Tranche B - September | Runcorn | £412M |
| | NHS National Proprietary Pharmaceuticals - Category | Runcorn | £300M |
| | ACCESS Pool Investment Manager for Real Estate - Global | Hampshire | £250M |
| | Employee Benefits & Services | Liverpool | £250M |
| | New Build Extension to the Existing Kent and Canterbury Hospital for the East Kent Hospitals University… | Canterbury | £232M |
| | NHS South of England Branded Medicines - Tranche A - September | Runcorn | £211M |
| | Insourcing / Outsourcing Clinical, Surgical and Diagnostic Procedures | Cardiff | £200M |
| | NHS Midlands and East Branded Medicines - Annual Tranche March | Runcorn | £200M |
| | NHS North of England Branded Medicines - Annual Tranche March | Runcorn | £190M |
| | NHS South of England Branded Medicines - Annual Tranche - September | Runcorn | £185M |
| | YORbuild3 Minor Works Contractors East Area | Beverley | £180M |
| | Robotic Surgical Equipment and Associated Accessories | Swillington | £160M |
| | Robotic Surgical Equipment and Associated Accessories Agile | Swillington | £160M |
| | Carlisle Southern Link Road | Carlisle | £150M |
| | International Healthcare Professionals Recruitment & Associated Services | Leatherhead | £150M |
| | Services at NHSS Hospitals - Insourcing DPS | Edinburgh | £150M |
| | Specialist Security Services | Birmingham | £150M |
| | Development Contractors Soft Market Testing | Boston | £148M |
| | NHS North of England Branded Medicines - Tranche B - March | Runcorn | £144M |
| | NHS Midlands and East Branded Medicines - Tranche B - March | Runcorn | £140M |
| | Homes England Multidisciplinary Technical Services Framework | Coventry | £130M |
| | Parking Enforcment and Car Park Management Services | Belfast | £110M |
| | NHS London Branded Medicines - Annual Tranche -September | Runcorn | £109M |
| | Apprenticeship Training to Soldiers of the British Army Though Service Provider Contracts Under the Army Apprenticeship… | Andover | £108M |
| | Cultural Heart Programme Zone 2 Library, Gallery & Museum, Food Hall, and Urban Park, Huddersfield Town… | Huddersfield | £105M |
| | Digital Identity Service Provider (IDSP) | West Malling | £100M |
| | Homes England Multidisciplinary Technical Services Framework | Bedford | £100M |
| | Modern Methods of Construction (MMC) New Homes Framework | Ystrad Mynach | £100M |
| | Improving Access to Psychological Therapy (IAPT) Services for NHS Nottingham & Nottinghamshire | Nottingham | £97M |
| | Delivered Official Controls in England and Wales | York | £93M |
| | Shaft & Silo Decommissioning Project | Thurso | £90M |
| | Prj_2574 - Recruitment | Worthing | £86M |
| | Supported Living for People With a Learning Disability, Mental Health Problem, Autism or a Physical/Sensory Impairment… | Carlisle | £86M |
| | NHS Midlands and East Branded Medicines - Tranche A - March | Runcorn | £82M |
| | NHS North of England Branded Medicines - Tranche A- March | Runcorn | £82M |
| | Document Management Solutions | Leicester | £80M |
| | M27 Junction 10 Improvement Scheme - G4_3_HCC_004 | Winchester | £80M |
| | Natural Gas (Supply and Export) | Reading | £70M |
| | SDF Lot 3.1 Central_ H W Martin (Traffic Management) LTD B | Birmingham | £70M |
| | Kirklees Cultural Heart Venue Operator Procurement | Huddersfield | £63M |
| | Kirklees Cultural Heart Venue Operator Procurement | Huddersfield | £62M |
| | Cultural Heart Programme, Zone 1 - Multi Storey Car Park and Venue, Huddersfield Town Centre | Huddersfield | £60M |
| | NHS National Proprietary Pharmaceuticals - Eculizumab Biosimilar | Runcorn | £60M |
| | MEICA National Operations Framework | Bristol | £59M |
| | Improving Access to Psychological Therapies in LLR | Leicester | £56M |
| | Kirklees Integrated Substance Misuse Service | Huddersfield | £55M |
| | Kirklees Integrated Substance Misuse Service | Huddersfield | £54M |
| | Decarbonisation Programme - Project CoPPA | London | £53M |
| | Multi-Temperature Distribution | London | £52M |
| | Scenes of Crime Consumables & Equipment (FCN) | Dorchester | £50M |
| | Electric Vehicle Charging Infrastructure | Paisley | £48M |
| | Museum of London - Annex Building Early Works | London | £45M |
| | National Grounds Maintenance and Extra Works Services | Newcastle upon Tyne | £43M |
| | Reopening of Flexible Framework for Early Learning and Childcare Places (New Entrants January | Paisley | £42M |
| | GP Out of Hours Service Across North West London Integrated Care Board | London | £41M |
| | Annexe Building Early Works | London | £40M |
| | Extra Care Housing - Care and Support | London | £36M |
| | Supplier Questionnaire for Multi Occupancy Accessible Transport (MOAT) Services | London | £35M |
| | Transport for Education and Social Services Related Contracts | Doncaster | £35M |
| | Call Off Against ESP Framework Ref 390- Document Management Solutions | Glenfield | £35M |
| | NHS Education With Leicestershire Partnership NHS Trust | Leeds | £34M |
| | NHS Education With Leicestershire Partnership NHS Trust | Leeds | £34M |
| | Cladribine (Mavenclad®) | Edinburgh | £34M |
| | NHS Education With South Warwickshire NHS Foundation Trust | Leeds | £32M |
| | NHS Education With South Warwickshire NHS Foundation Trust | Leeds | £32M |
| | Syria Education Programme II | London | £31M |
| | Cambridge City Council - Action on Energy Cambridgeshire Retrofit Framework | Cambridge | £30M |
| | Parachute Packing and Maintenance in the South West USA | Bristol | £30M |
| | Police Records Management System (RMS) | Manchester | £30M |
| | Improving the Teaching of Physical Education at Primary School | London | £30M |
| | 3FE - Design Team Consultancy Services (Multi-Disciplinary Design Team, Principal Designer (CDM) Project Information Manager (BIM… | Aylesbury | £28M |
| | Protector Training Conduct | Bristol | £26M |
| | Municipal Waste Haulage Service | Durham | £25M |
| | NHS Education With George Eliot Hospital NHS Trust | Leeds | £22M |
| | NHS Education With George Eliot Hospital NHS Trust | Leeds | £22M |
| | Cloud Services - Application Development and Operational Support | London | £21M |
| | Laurence Calvert Academy - Main Works | Manchester | £20M |
| | Flexible Resource Pool - National | Leeds | £20M |
| | Employee Support Provider 2 | Huntingdon | £20M |
| | Licenses to Norfolk County Council | Norwich | £20M |
| | Sustainable Healthcare Waste Management: Minimisation, Repurposing & Recycling Services | London | £20M |