| | DS/DN - Greater Manchester Pharmacy Logistics Supply Chain Service | Manchester | £7B |
| | Greater Manchester Pharmacy Logistics Supply Chain Service | Manchester | £7B |
| | Total Facilities Management 2022 Framework | London | £6B |
| | G-Cloud 13 | Liverpool | £4B |
| | G Cloud 13 (Lots 1, 2 & 3) | Liverpool | £4B |
| | Back Office Systems, Services and Support Framework Agreement | Portsmouth | £2B |
| | ID Manchester | Manchester | £2B |
| | LCC Transport DPS | Lincoln | £2B |
| | Pharmaceutical Wholesaler Services | London | £1B |
| | Fuel Cards and Associated Services | Liverpool | £1B |
| | G-Cloud 13 Lot 4 | Liverpool | £1B |
| | NHS South of England Branded Medicines - Tranche B and Annual | Runcorn | £876M |
| | Energy Recovery Facility (ERF) Construction Works Including All Buildings, Infrastructure and Works for the North London… | London | £799M |
| | Joint Venture for the Alton Estate Regeneration | London | £700M |
| | Energy Recovery Facility ('ERF') Construction Works Including All Buildings, Infrastructure and Works for the North London… | London | £683M |
| | Advance Purchase Agreement for Influenza Pandemic Specific Vaccines | London | £676M |
| | APA for Influenza Pandemic Specific Vaccines | Runcorn | £676M |
| | Insurance & Related Services 4 (IS4) | Liverpool | £600M |
| | Education Network for Northern Ireland — “Education Network (NI)” | Belfast | £513M |
| | Medical Retinal Vascular Treatments | Runcorn | £450M |
| | EA Strategic Partner Services and Schools Management System Solution | Belfast | £406M |
| | Highways Delivery Partner | Ellesmere Port | £400M |
| | NHS South of England Branded Medicines - Tranche B and Annual | Runcorn | £314M |
| | Multi Modality Imaging Equipment and Maintenance Framework | Edinburgh | £300M |
| | Fund Disbursement: Grants & Loans | Liverpool | £280M |
| | Invitation to Offer for NHS London Branded Medicines - Tranche A and Annual | Runcorn | £277M |
| | HIV and Preventative Treatments | London | £270M |
| | Support at Home - Spot Providers | Hertford | £267M |
| | Highways and Transport Services Framework | Ealing | £224M |
| | NHS Education Birmingham City University | Leeds | £215M |
| | NHS Education Birmingham City University | Leeds | £215M |
| | BHCC JB Highways Services Contracts | Brighton | £200M |
| | RHP - Asset Management Contracts | Teddington | £155M |
| | Microbiology Serology & Ancillary Services | Bristol | £150M |
| | Microbiology Serology and Ancillary Services | Bristol | £150M |
| | Online Programme Management Services for Southampton's Global Online Programmes | Southampton | £150M |
| | Accounting Services Programme (ASP) | Bangor | £127M |
| | Hawk Future Engines Support Solution | Bristol | £120M |
| | NHS London Branded Medicines - Tranche A and Annual | Runcorn | £114M |
| | Home Office Self Isolation Checks | London | £114M |
| | Carbon Zero Initiatives - Consultancy | Bolton | £100M |
| | Door Entry, Access Control, CCTV and Warden Call Installs and Maintenance | Alfreton | £100M |
| | Door Entry, Access Control, CCTV and Warden Call Installs and Maintenance Framework | Derbyshire | £100M |
| | LB Havering Complex Placements Framework - Round 22 | Romford | £100M |
| | Managed Stores & Materials Replenishment Solution | Castleford | £100M |
| | Renewable Energy Initiatives | Bolton | £100M |
| | Zero Carbon Initiatives - Works | Bolton | £100M |
| | Pan-London Home Oxygen Service | London | £97M |
| | Supported Living for People With a Learning Disability, Mental Health Problem, Autism or a Physical/Sensory Impairment… | Carlisle | £86M |
| | Continence Pads & Garments | Edinburgh | £86M |
| | Grounds Maintenance Framework Notice | Prescot | £85M |
| | Development at Elwick Place, Ashford, Kent | Ashford | £80M |
| | Fertility and Other Gynaecology Services in Leeds | Leeds | £80M |
| | Intrusive Surveys Framework Restoration and Renewal Programme | London | £80M |
| | Library Stock | Leicester | £75M |
| | Dispensing Facilities and Overlabelling Service of Pre-Packed Medicines | Bristol | £73M |
| | Oxford Phase 2 Works - Botley Bridge, Platform 5, Track & Crossovers | London | £65M |
| | Ground Ambulance to BATUK Notice | Warminster | £65M |
| | Cleaning Materials & Janitorial Supplies | Leicester | £60M |
| | Sandwiches and Associated Products | Manchester | £60M |
| | Residual Waste Treatment and Disposal 2021 - CPwN | Inverness | £58M |
| | CfT - C1110 Customer Billing and Contact (CBC) Renewal and Implementation Programme | Belfast | £55M |
| | Ground Ambulance to BATUK | Warminster | £54M |
| | Projects 10028504, 10028371, 10028205, 10028149, 10027904, 10027789, | Swindon | £51M |
| | Electricity and Gas Utilities to Essex County Council | Chelmsford | £50M |
| | Development at Friar's Close, Bear Lane and 1 and 3 Burrell Street, London | Liverpool | £50M |
| | Pharmaceutical Wholesale Services | Fulbourn | £50M |
| | Animal Health Sciences Building Market Engagement Questionnaire | Belfast | £48M |
| | Cambridge City Council - Planned Maintenance | Cambridge | £48M |
| | Prior Information Notice - HIF Rail Works Packages | Chatham | £48M |
| | Oracle Servers | Exeter | £47M |
| | Children's Residential Care | Dorchester | £42M |
| | Community Equipment Service (BNSSG CCG, Bristol City Council, North Somerset Council & South Gloucestershire Council) | Weston Super Mare | £42M |
| | Library Stock | Leicester | £41M |
| | Metropolitan Police Service Construction Professional Services Framework -FAT Publication Ref: 2021/S 000 | London | £40M |
| | Materials Supply and Managed Service | Norwich | £38M |
| | Recycling Centre Haulage and Container Maintenance | Hertford | £36M |
| | Software Reseller | Edinburgh | £36M |
| | Joint Command and Staff Training (JCAST) | Bristol | £35M |
| | Building & Construction Works for a New Leisure Centre in West Drayton | Uxbridge | £33M |
| | Intrusive Surveys Framework Restoration & Renewal Programme | London | £32M |
| | 3rd Party Logistics | Wakefield | £32M |
| | GM Collaboration - HR/Payroll System GMCA 400 | Salford | £31M |
| | DDaT Central Data Services Partner Service | London | £30M |
| | Insulin Pumps, Cgm, Associated Consumables and Technology | None | £30M |
| | Dynamic Purchasing System - Temporary Accommodation | Hillingdon | £29M |
| | Supported Living Care Provision in Torbay | Torquay | £27M |
| | Call Off Microsoft Enterprise License Agreement Re-Seller | Newcastle upon Tyne | £26M |
| | OH and Associated Wellbeing Services for Health | Hemel Hempstead | £25M |
| | PVCu Windows, Composite Doors and Associated Brickwork Repairs | Dudley | £25M |
| | Healthy Child Programme 0-19 for London Borough of Redbridge | Ilford | £24M |
| | Leisure Services | Market Harborough | £24M |
| | Temporary Chemical Dosing | Glasgow | £24M |
| | Personal Protective Equipment for Healthcare Workers for the Care of Patients With Suspected or Confirmed Novel… | London | £23M |
| | Homicide Services - 2023 | London | £23M |
| | Community Dental Services | Durham | £22M |
| | Depot Plant Replacement | London | £22M |
| | Community Dental Services | Preston | £22M |
| | Carriageway and Car Park Resurfacing / Reconstruction and Minor Repairs 2022 | Motherwell | £20M |
| | DDaT Central Security Architecture | London | £20M |