| | Construction Works and Associated Services 2 / Procure 23 (CWAS2/P23) | Liverpool | £30B |
| | Medical Examination Gloves and Surgical Gloves | London | £6B |
| | Direct Oral Anticoagulants (DOACs) for the NHS in England | London | £3B |
| | Interventional Cardiology, Radiology and Neuroradiology, CRM & EP | London | £3B |
| | Children's Residential Placements - Consortia Commissioning - Framework Third Re-Opening July | Southampton | £2B |
| | Lower Thames Crossing - Kent Roads and Roads North of the Thames | Bedford | £2B |
| | Modular Building | Salford | £2B |
| | Tender Round 8 (TR8) for the Grant of One Offshore Transmission Licence | London | £1B |
| | New Build Housing Construction Framework | Uxbridge | £1B |
| | Facilities Management Services to COVID-19 Testing Sites 1 | Liverpool | £889M |
| | Facilities Management Services to COVID-19 Testing Sites 2 | Liverpool | £752M |
| | Grounds Maintenance 21-31 | Sunderland | £678M |
| | Debt Resolution Services | Liverpool | £645M |
| | Facilities Management Services to COVID-19 Testing Sites 3 | Liverpool | £615M |
| | Health Professional Education and Training Services (Phase 1) | Cardiff | £612M |
| | SEND School Expansions | Leicester | £571M |
| | Managed Services | West Malling | £500M |
| | Facilities Management Services to COVID-19 Testing Sites 4 | Liverpool | £479M |
| | Heathrow and Derwentside IRCs Procurement | London | £461M |
| | Human Normal Immunoglobulin and Anti-D Immunoglobulin | Runcorn | £450M |
| | YORbuild3 Medium Works Contractors West Area | Leeds | £400M |
| | Finance and Leasing DPS | Hertford | £260M |
| | Barrister Services | West Malling | £250M |
| | YORbuild3 Medium Works Contractors East Area | Beverley | £240M |
| | Intravenous Fluids, Topical Solutions, Urological Solutions and Gelatins | Runcorn | £191M |
| | Modular Pumping Stations | Glasgow | £175M |
| | CHIC Compliance Audit Services Framework | Birmingham | £150M |
| | Development Management Partner | Huyton | £128M |
| | Home Antibody Testing Service | London | £124M |
| | General Laboratory Equipment and Associated Post Installation Services | London | £120M |
| | Laboratory Equipment (General) and Associated Post Installation Services | London | £120M |
| | Cobas Reagent | London | £116M |
| | Defence Strategic Radio Services (DSRS) | Wiltshire | £108M |
| | Delivery Partner Dynamic Purchasing System (V2) | Newcastle upon Tyne | £100M |
| | Highways Maintenance | Hackney | £100M |
| | LB Havering Complex Placements Framework - Round 14 | Romford | £100M |
| | Supported Living Services for Individuals With a Learning Disability, Autistic Spectrum Conditions and/or Mental Health Conditions… | Stafford | £94M |
| | Non-Emergency Patient Transport Services (NEPTS) | Winchester | £90M |
| | Modification Notice to Covid-19 Test Digital Platform | Leeds | £75M |
| | Polymer Aprons | Sheffield | £70M |
| | Framework for Standard Home Care Services | Derby | £63M |
| | Chemical Dosing Equipment | Glasgow | £62M |
| | NHS England and NHS Improvement (East) — Cambridgeshire Prisons, Claire Lodge SCH and Dental Services at… | Cambridge | £61M |
| | Children's Residential Care, Fostering and Therapeutic Education Service | Taunton | £60M |
| | UKBC Laboratory Agreement | London | £50M |
| | Health & Social Care Equipment and Associated Services | Wakefield | £50M |
| | Local Energy Consultancy Framework | London | £50M |
| | Net Zero Carbon or Low Carbon Housing Developments- PIN and Market Engagement | Wokingham | £50M |
| | RN Data Integration Partner - CCS Framework Call Off | Portsmouth | £50M |
| | DHSC T&T Central Portfolio and Rapid Response Teams | London | £49M |
| | National Professional Qualifications Delivery Call Off Cohort | London | £41M |
| | Heart of the City II - Block H | Sheffield | £38M |
| | Marina Centre and Phoenix Pool & Gym Leisure Management | Great Yarmouth | £36M |
| | Ambulance Auxiliary Support PIN | Leeds | £34M |
| | York Way Redevelopment CF | London | £33M |
| | Internal Refurbishment Programme | Sunderland | £32M |
| | Cleaning Services | London | £30M |
| | EA Integrated Financial Management Information System Inc. HR/Payroll (The iFS Project) | Belfast | £29M |
| | Skills Training in the Automotive Sector — DPS for Skills Providers and Training Provision, Skills for… | Chester | £27M |
| | Covid-19 Various Campaign Services | London | £27M |
| | Design and Build of a 5G Network in Basing View, Basingstoke | Basingstoke | £25M |
| | Erasmus+ and ESC Residual Services and Temporary Worker Visa Sponsorship Services (Tier 5) | London | £24M |
| | Cat 1 - Software and Licencing | Cheshire | £24M |
| | Test and Trace Service Evaluation for Covid-19 Testing | London | £22M |
| | ICT Managed Workplace Services | North Wales | £21M |
| | Recruitment and Management of Childrens Agency Social Workers | West Midlands | £20M |
| | Support to Phase 2 of RWM Plutonium Integrated Project | Didcot | £19M |
| | Procurement and Supply Chain Delivery Partner (PDP) | Birmingham | £19M |
| | 16+ Semi-Independent Accommodation & Support Services to Looked After Children and Care Experienced Young Adults in… | Walthamstow | £16M |
| | Alternative Education | West Midlands | £16M |
| | F-35 and F-76 - Not an Opportunity | Bristol | £16M |
| | Civil Parking Enforcement and Management Services for Durham County Council | Durham | £16M |
| | Glasgow Family Support | Glasgow | £16M |
| | Hard Facilities Management Service | Liverpool | £16M |
| | Berkeley Blower House Remediation | Thornbury | £15M |
| | NHS England and NHS Improvement Mobile Telephony | Leeds | £15M |
| | CSSF Lebanon: British Policing Support Programme | London | £15M |
| | Electrical Appliances | Leicester | £14M |
| | Sleeping Systems | Bristol | £14M |
| | Temporary Power and HVAC | Birmingham | £13M |
| | Temporary Power & HVAC | Birmingham | £13M |
| | Roche Liat Cobas V Kit & Chemicals | London | £12M |
| | ICT Enterprise Systems Services | North Wales | £12M |
| | Microsoft Enterprise Agreement | Sheffield | £12M |
| | School Health Nursing and Child Vision Screening Services | West Midlands | £11M |
| | Vehicle Parts Managed Service | Dorchester | £10M |
| | Specialist Mental Health Housing and Support Service | York | £10M |
| | Bulk Paper Printing Solution, Ancillary Equipment With Support and Maintenance | Swansea | £10M |
| | Collaborative Robots (COBOTS) | Hampshire | £10M |
| | Covid-19 Campaign Services | London | £10M |
| | Liquified Petroleum Gas & Other Liquified Fuels | Leicester | £10M |
| | Primary Care Musculoskeletal Physiotherapy Service to NHS Berkshire West Clinical Commissioning Group | Reading | £9M |
| | Somerset West and Taunton - Seaward Way Minehead | Devizes | £9M |
| | Belle Isle Tenant Management Organisation (BITMO) Responsive and Planned Repairs and Maintenance Works, Minor Refurbishment Works… | Leeds | £9M |
| | Dismounted Situational Awareness (DSA) Design and Integration Partner (D&IP) | Bristol | £9M |
| | Print Production and Logistics Managemen | Birmingham | £9M |
| | ICT Enterprise Communication Services | North Wales | £8M |
| | HMPO DAP Development Services | Croydon | £8M |
| | Minding the Gap | London | £8M |
| | Forensic Audit Framework | Birmingham | £8M |