| | Digital Document Solutions | London | £5B |
| | Workforce Improvement Services | Cambridge | £5B |
| | Functional Assessment Services FAS | Sheffield | £3B |
| | Waste Management DPS - LPP/2021/004 | London | £2B |
| | Waste Management Dynamic Purchasing System | London | £2B |
| | NHS for Branded Medicines - National | Runcorn | £2B |
| | Bath Clean Air Zone (CAZ) Financial Assistance Scheme | Bath | £2B |
| | Planned Investment and Building Safety Works - Market Engagement Opportunity | London | £1B |
| | New Build Construction Framework | London | £1B |
| | Fuel Cards and Associated Services | Liverpool | £1B |
| | Domiciliary Care Framework | Bromley | £1B |
| | Construction Professional Services | Liverpool | £1B |
| | Insulation and Associated Works Framework | Alfreton | £950M |
| | Decontamination Services and Solutions | Hemel Hempstead | £500M |
| | Food & Drink | Liverpool | £500M |
| | Highway Civils Framework | Maidstone | £500M |
| | Highways Delivery Partner | Ellesmere Port | £400M |
| | Highways Delivery Partner 2022 | Ellesmere Port | £400M |
| | Childrens Residential & Foster Care Placements | Widnes | £336M |
| | South Thamesmead Phases 2 and 3 Joint Venture Partnership | London | £300M |
| | Wiltshire Highways Maintenance | Trowbridge | £300M |
| | Highway Civils Framework | Maidstone | £250M |
| | Patient/Citizen Communications & Engagement Solutions | Salford | £250M |
| | Internal and External Refurbishment Works Programme | London | £210M |
| | Homecare Medicines Services | Fulbourn | £200M |
| | Pharmacy Robots, Inventory Management Systems, Assets, and Associated Services | Leatherhead | £200M |
| | NHS Education With Sheffield Teaching Hospitals NHS FT | Leeds | £162M |
| | NHS Education With Sheffield Teaching Hospitals NHS FT | Leeds | £162M |
| | Waste Collection Services on Behalf of Warwick District Council and Stratford-on-Avon District Council | Leamington Spa | £160M |
| | Framework for Stairlifts, Lifting Equipment and Property Adaptations | Sunderland | £150M |
| | Magnox - HP3 Qualification - Cat 1: Health Physics Professional Resource | Thornbury | £107M |
| | Magnox - HP3 Qualification - Cat 3: Health Physics Monitoring Resources (With Portable Metrology) | Thornbury | £107M |
| | Voice, Video and Integration (VVI) Services | London | £105M |
| | Huguenot House Redevelopment: Soft Market Testing | London | £100M |
| | Reopening of Approved Provider List for Home and Community Support Lots 2 & 3 (2021/ | London | £84M |
| | Devices for Remote Learning and Schools | Liverpool | £71M |
| | Fund Manager | Cardiff | £65M |
| | Back Office Systems, Services and Support Framework Agreement | Portsmouth | £64M |
| | Cleaning Materials & Janitorial Supplies | Leicester | £60M |
| | Framework an Integrated Community Equipment Service for the London Borough of Redbridge and Participating Authorities | Ilford | £60M |
| | Higher Education Networking Supply & Services 2 | Leeds | £60M |
| | NHC Simple Tenants Contents Insurance 22 - 26 | Sunderland | £60M |
| | NHS Education South Tees Hospitals NHS FT | Leeds | £56M |
| | NHS Education South Tees Hospitals NHS FT | Leeds | £56M |
| | Community Elective Services in Oldham | Oldham | £56M |
| | Architecture + Urbanism Framework | London | £55M |
| | BBC Birmingham Property Developer | London | £50M |
| | Landscape Maintenance Services | London | £45M |
| | Low Carbon Heat to the Seaham Garden Village via a District Heating Network | Durham | £45M |
| | Royal Air Force (RAF) Centre of Aviation Medicine (CAM) Relocation | Bristol | £45M |
| | Tech Scalers | Glasgow | £42M |
| | Digital Delivery Centre Support for New HMRC Services | Salford | £40M |
| | Phalanx Close in Weapons System in-Service Support | Bristol | £40M |
| | Domestic Contact Tracing and Enquiries, Feedback & Complaints Delivery - Lot C | London | £37M |
| | Finder Opportunity VTN | Bristol | £36M |
| | Electronic Prescribing and Medicines Administration Services | Cardiff | £35M |
| | Highway Works | Bedford | £35M |
| | Sunderland Eye Infimary | Sunderland | £34M |
| | DfI Roads and Rivers T-1118 Interim Term Contracts for Asphalt Resurfacing Phase 1 | Belfast | £33M |
| | Test and Trace Delivery Partners for Trace, Contain & RTTS Portfolio - Lot A | London | £30M |
| | Food Sector Development Framework Agreement | Cardiff | £30M |
| | High Level Wear Footbridge and Associated Works | Sunderland | £30M |
| | NHS Education North Tees & Hartlepool NHS FT | Leeds | £30M |
| | NHS Education North Tees & Hartlepool NHS FT | Leeds | £30M |
| | NHS Education Lancashire Care NHS Foundation Trust | Leeds | £29M |
| | NHS Education Lancashire Care NHS Foundation Trust | Leeds | £29M |
| | NHS Education Tees Esk & Wear Valley NHS FT | Leeds | £28M |
| | NHS Education Tees Esk & Wear Valley NHS FT | Leeds | £28M |
| | Supported Living and Indepedent Living ( Extra Care Housing) Dynamic Purchasing System | Norwich | £27M |
| | Trace, Contain & RTTS Delivery Partner - RTTS Integration Delivery - Lot B | London | £25M |
| | Outsourced Kitting Production | London | £25M |
| | Modular Modern-Methods of Construction Projects Framework Agreement | Stafford | £25M |
| | NHS Education With the Hillingdon Hospital NHS Trust | Leeds | £25M |
| | NHS Education With the Hillingdon Hospital NHS Trust | Leeds | £25M |
| | DUD - Gas Central Heating and Boiler Replacement | Dudley | £24M |
| | Well Street, Buckley, Development of 140 Properties | St Asaph | £24M |
| | Appointment of a Contractor for a Residential Development at Grange Park, Blackpool, FY3 7PH | Blackpool | £22M |
| | Community Life Choices for Leicestershire | Leicester | £22M |
| | Technical & Transition Partner | London | £22M |
| | Appointment of a Contractor for a Residential Development at Grange Park, Blackpool, FY3 7PH | Blackpool | £22M |
| | NHS Education Leeds York Partnership NHS FT | Leeds | £21M |
| | New Education Leeds York Partnership NHS FT | Leeds | £21M |
| | Digital Payment Solution Framework | London | £20M |
| | Linen and Laundry Services | Barnstaple | £20M |
| | Stationery and Copier Paper | Caerphilly | £20M |
| | WD2 - PVC-U and Timber Windows and Doors | Uxbridge | £20M |
| | WD2 - PVC-U and Timber Windows and Doors Framework | Uxbridge | £20M |
| | Passenger Assistants - ASCHIW/2021/111* | Stoke on Trent | £20M |
| | Modular Build Theatres & Elective Surgical Ward | Nottingham | £19M |
| | Borders & International and Contain CRM Delivery - Lot D | London | £18M |
| | Greenwich Mental Health Alliance | London | £18M |
| | Outsourced Kitting Production | London | £18M |
| | Devices for Remote Learning and Schools | Liverpool | £16M |
| | IUPC Laboratory Gases and Associated Equipment Framework Agreement | Reading | £16M |
| | A1/Queen Margaret University Junction Construction Works | East Lothian | £15M |
| | Security Services | Leeds | £14M |
| | Abbott Alinity M PCR Reagents_31 March | London | £14M |
| | Electronic Treadles | London | £13M |
| | Edinburgh's Blended Employability Services | Edinburgh | £13M |
| | MP3A Framework and Stable Block | Rotherham | £12M |