| | Construction Works and Associated Services | Liverpool | £30B |
| | Technology Services 3 | Liverpool | £2B |
| | Collaborative Recruitment Services Contingent Labour and Permanent Recruitment | London | £840M |
| | Strategic Energy and Asset Management Performance Framework (SEAM) | Newcastle upon Tyne | £750M |
| | Services Related to COVID-19 | Newport | £710M |
| | Technology Services 3 | Liverpool | £580M |
| | Highways England Operational Technology Commercial Framework | Guildford | £500M |
| | Ilford Western Gateway JV Partnership | Ilford | £500M |
| | Midland Mainline Electrification Phase 3 - Market Engagement PIN & Invitation to Market Engagement Briefing | London | £500M |
| | Operational Technology Commercial Framework | Guildford | £500M |
| | Special Partnership Trust - Cleaning Tender Lot 2 - Cleaning and Caretaking | St Clement Truro | £500M |
| | Care and Support Services at Furlong Close, Wiltshire | Trowbridge | £469M |
| | Disposable and Washable Continence Care and Associated Products | Sheffield | £395M |
| | High Speed Two (HS2) Limited, Phase Two - For Phase Two Route Wide Ground Investigation | Birmingham | £300M |
| | Integrated Health and Wellbeing Services to Prisons in the South West Region | Bristol | £273M |
| | Online Distance Learning for UOR Including Henley Business School | Reading | £250M |
| | Multi Temperature Food Solutions | London | £240M |
| | High Speed Two (HS2) Limited, Phase Two - For Phase Two Route Wide Ground Investigation -… | Birmingham | £215M |
| | Minor Building Works | Telford | £200M |
| | Multi Temperature Food Solutions | London | £196M |
| | Future Defence Infrastructure Services (FDIS) - Regional Accommodation Maintenance Services SOUTH WEST | Andover | £145M |
| | Future Defence Infrastructure Services (FDIS) - Regional Accommodation Maintenance Services SOUTH EAST | Andover | £145M |
| | Northamptonshire Independent Fostering Agency and Children's Homes for Children in Care | Northampton | £144M |
| | Future Defence Infrastructure Services (FDIS) - National Accommodation Management Services | Andover | £141M |
| | Professional Consultancy Services | Telford | £140M |
| | Electricity | Cardiff | £138M |
| | Anaesthesia Machines, Ventilator Equipment and Related Accessories and Services | London | £136M |
| | Anaesthesia Machines, Ventilator Equipment and Related Accessories & Services | London | £136M |
| | National for Waste Management and Minimisation | Chester | £136M |
| | Project 86 Mental Health Rehabilitation and Transforming Care Programme Dynamic Purchasing System | Stoke on Trent | £124M |
| | Project 86 Mental Health Rehabilitation and Transforming Care Programme Dynamic Purchasing System - Expressions of Interest… | Stoke on Trent | £124M |
| | Future Defence Infrastructure Services (FDIS) - Regional Accommodation Maintenance Services CENTRAL | Andover | £124M |
| | Technology Enabled Care (TEC) Products and Services | Leicester | £120M |
| | Goods and Services to Support the UK Covid-19 Testing Strategy | London | £114M |
| | Modular/Pre-Fabricated Modular Buildings Solutions | Dorking | £100M |
| | Place, Connectivity and Infrastructure Professional Services Collaborative Framework 2022 | Winchester | £100M |
| | Place, Connectivity & Infrastructure Professional Services Framework 2022 | Hampshire | £100M |
| | Temporary Agency Resources Managed Services | London | £100M |
| | Facilities Management | Reading | £98M |
| | High Speed Two (HS2) Limited, Phase Two - For Phase Two Route Wide Ground Investigation -… | Birmingham | £85M |
| | Future Defence Infrastructure Services (FDIS) - Regional Accommodation Maintenance Services NORTH | Andover | £82M |
| | DSD Medical Support Services | Belfast | £82M |
| | Office Furniture Solutions and Associated Services | Wakefield | £75M |
| | Secondary Mental Health Services at HMP Altcourse | Preston | £72M |
| | Evidence Fund | East Kilbride | £72M |
| | Leeds Housing Responsive Repairs, Voids Cyclical Maintenance Services (West) | Leeds | £70M |
| | Soft Facilities Management Services | London | £70M |
| | Cumbria Addictions Service - South | Carlisle | £70M |
| | West Sussex Electric Vehicle Chargepoint Network | Chichester | £68M |
| | Framework an Integrated Community Equipment Service for the London Borough of Redbridge and Participating Authorities | Ilford | £60M |
| | Southern Housing - Fire Safety Works Term Contracts | London | £60M |
| | Specialised Services in Care Homes | Carlisle | £60M |
| | Community Support Service | Irvine | £56M |
| | 55 000 000 | Sheffield | £55M |
| | Environmental Decontamination | London | £55M |
| | Framework for Home Care Services in Herefordshire | Hereford | £55M |
| | Black Country Framework for Minor Works | West Midlands | £50M |
| | Employee Support Services and Benefits | West Malling | £50M |
| | Interim Indirect Fires Simulation 701554451 (TSSP/128) - CF Opportunity | Bristol | £50M |
| | Care and Support Services at Furlong Close, Wiltshire | Trowbridge | £47M |
| | Interventional Radiology Products | Belfast | £45M |
| | DNO-Whd/025 Transfer of Up to 5000 Drums of Higher Activity Waste (HAW) | London | £42M |
| | Spares for the Armoured Tracked and Light Wheels Platforms | Telford | £41M |
| | Spares for the Armoured Tracked and Light Wheels Platforms and Associated Items | Telford | £41M |
| | EKFB JV - Acoustic Barrier Supply and Installation - NEC Sub Works | Birmingham | £40M |
| | Neighbourhood Planning Support Services VARIATION | London | £37M |
| | Public Sector Resourcing (PSR) | Manchester | £36M |
| | Print Services | London | £34M |
| | Major Projects Leadership Academy | London | £31M |
| | Major Projects Leadership Academy (MPLA), Orchestrating Major Projects (OMP) & Optional Services | London | £31M |
| | Public Health England - Weight Management Services | London | £30M |
| | River Restoration & Associated Works | Reading | £30M |
| | Housing Support Solutions for Homeless Households | Liverpool | £29M |
| | Maritime Aerial Patrols | Southampton | £28M |
| | SLC Training and Employability Framework | Hamilton | £28M |
| | Investments in Forests and Sustainable Land Use - Amendment No 3 | East Kilbride | £28M |
| | Council Housing Electrical Upgrade Programme Phase 2 | Sheffield | £27M |
| | Telemetry Engineering Support Services | Glasgow | £27M |
| | Provision, Operation and Maintenance of Electric Vehicle Charging Infrastructure for General Public Use | Cardiff | £25M |
| | Future Network for Schools (FN4S) Service for Educational Establishments in Hampshire and Southampton | Winchester | £25M |
| | Medium Weight Adaptable Rescue Pumps | Cambuslang | £25M |
| | Royal Wolverhampton NHS Trust - Main Contractor Framework D3 | Wolverhampton | £25M |
| | E-Disclosure and Review Services | Liverpool | £24M |
| | Disposable Cubicle Shower and Window Curtains | Sheffield | £24M |
| | NHS Education With South West London & St Georges Mental Health Trust | Leeds | £24M |
| | NHS Education With South West London & St Georges Mental Health Trust | Leeds | £24M |
| | Interim Surface Finish | London | £22M |
| | Early Intervention and Prevention Pseudo Dynamic Purchasing System (DPS) | Peterborough | £21M |
| | West Midlands Combined Authority AEB Digital Bootcamps | Birmingham | £21M |
| | Custody Medical Healthcare Services | Guildford | £20M |
| | EKFB JV - Precast Concrete Panels Forming Part of Route Wide Acoustic Barrier - NEC Sub… | Birmingham | £20M |
| | Land Environment Air Picture Provision (LEAPP) Obsolescence | Bristol | £20M |
| | Medically Managed Inpatient Detoxification for People With Drug and or Alcohol Problems | Stafford | £20M |
| | Medically Managed Inpatient Detoxification Service | Stafford | £20M |
| | Temporary Accomodation - Cabins | Birmingham | £20M |
| | Temporary Traffic Management | Birmingham | £20M |
| | Waterproofing and Firestopping to Precast Concrete Cut and Cover Tunnels | Birmingham | £20M |
| | Passenger Assistants - ASCHIW/2021/111* | Stoke on Trent | £20M |
| | Transporting Vulnerable Children and Adults - ASCHIW/2021/111* | Stoke on Trent | £20M |
| | Investments in Forests and Sustainable Land Use - Amendment No 1 | East Kilbride | £19M |