| | Schools and Community Buildings — England | Uxbridge | £6B |
| | SCF Residential Delivery and Development Framework | Exeter | £5B |
| | Gigabit Infrastructure Subsidy Programme - Dynamic Purchasing System (DPS) | London | £2B |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £2B |
| | National Framework for Civils and Infrastructure | Gateshead | £2B |
| | Planned Investment & Regeneration Major Works | London | £1B |
| | Building Safety and Compliance Framework | Prescot | £880M |
| | HS2 Phase 2a Design and Delivery Partner | Birmingham | £500M |
| | Pathology Managed Service Across South Yorkshire and Bassetlaw | Sheffield | £500M |
| | Planned Investment & Regeneration Major Works | London | £410M |
| | Dynamic Purchasing System (DPS) for Health and Social Care. DPS 3 - Independent Living | Croydon | £350M |
| | Project VIRTUS | Bristol | £350M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £312M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £309M |
| | C17 Synthetic Training Service | Bristol | £274M |
| | M5 Junction 10 Improvements Scheme | Gloucester | £254M |
| | Barrister Services | West Malling | £250M |
| | Wound Closure Products | London | £240M |
| | Future Theory Test Service (FTTS) Test Centre Network (TCN) | Nottingham | £231M |
| | Advanced Wound Care | London | £226M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £212M |
| | Area 3 Maintenance and Response | Guildford | £204M |
| | Major Building Works | Telford | £200M |
| | Minor Building Works | Telford | £200M |
| | PIN Notice Workforce and Wellbeing Services - Absence Management, Occupational Health, Employee Assistance Programmes and Eyecare… | Salford | £200M |
| | PIN Notice: Workforce and Wellbeing Services - Absence Management, Occupational Health, Employee Assistance Programmes and Eyecare… | Salford Quays | £200M |
| | Workforce and Wellbeing Services - Absence Management, Occupational Health, Employee Assistance Programmes and Eyecare Services | Salford Quays | £200M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £176M |
| | PfH Scotland Whole House Refurbishment Framework | Edinburgh | £150M |
| | Torus Development Contractors Framework — Lot 2: GBP 10 000 000+ | Liverpool | £150M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £147M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £144M |
| | Professional Consultancy Services | Telford | £140M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £135M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £131M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £127M |
| | Operational Ration Packs | Bristol | £126M |
| | Residential and Nursing Care and Accommodation for Older People, and People With Mental Health and Physical/Sensory… | Sale | £123M |
| | CSKL & TPPL Vehicle Rental Framework | West Malling | £120M |
| | Technology Delivery Framework | Coventry | £120M |
| | Pressure Area Care and Patient Handling Including Beds and Associated Products Rental and Decontamination | Nottingham | £112M |
| | Consultancy & Skilled Persons Framework | London | £110M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £107M |
| | Advanced Wound Care | London | £107M |
| | Middlegate Water Treatment Works | Peterborough | £100M |
| | Building Maintenance & Refurbishment Services Framework | London | £95M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £81M |
| | Secure Delivery International | London | £72M |
| | Supported Living and Residential Care for Adults With a Learning Disability in the London Borough of… | Richmond upon Thames | £72M |
| | Main Contractor for Stephenson Building Refurbishment (Stage 2) | Newcastle upon Tyne | £65M |
| | Torus Development Contractors Framework — Lot 1: GBP 0-GBP 10 000 000 | Liverpool | £65M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £63M |
| | A303 Stonehenge (Amesbury to Berwick Down) - Delivery Assurance Partner | Birmingham | £60M |
| | A303 Stonehenge (Amesbury to Berwick Down) Delivery Assurance Partner | Bristol | £60M |
| | TfL 95743 Contact Centres Outsourced Services FWC | London | £60M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £59M |
| | Frameworks for Consultancy Services for Belfast, Northern, South Eastern, Southern and Western Health and Social Care… | Belfast | £57M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £56M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £55M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £50M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £48M |
| | Marchwood Port Development - Phase 1-3 Design and Build | Grimsby | £45M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £41M |
| | Spares for the Armoured Tracked and Light Wheels Platforms and Associated Items | Telford | £41M |
| | CSKL & TPPL Vehicle Rental Framework | West Malling | £40M |
| | Defra Opportunity for Research Development and Evidence Framework 2 | Bristol | £40M |
| | Defra Research Development and Evidence Framework 1 | London | £40M |
| | Fostering Agency Placements Flexible Agreement - Provider Engagement Event | Preston | £40M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £40M |
| | NHS Education With Homerton University Hospital NHS Foundation Trust | Leeds | £38M |
| | NHS Education With Homerton University Hospital NHS Foundation Trust | Leeds | £38M |
| | NHS Education With Central & North West London NHS Foundation Trust | Leeds | £36M |
| | NHS Education With Central & North West London NHS Foundation Trust | Leeds | £36M |
| | Fire-Related Works Framework | Wembley | £32M |
| | HART Fleet Vehicles 3rd Generation | Brierley Hill | £32M |
| | Construction and Conversion of Passenger Vehicles [3193391] | Ballymena | £31M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £30M |
| | Purchases of Single Use Theatre Protective Clothing | Leeds | £30M |
| | Cairnryan Inland Border Facility | Glasgow | £30M |
| | Legal Services | London | £30M |
| | Mail Services | Leeds | £30M |
| | NICE Guideline Development Centres | London | £30M |
| | Windows and Doors | Glenrothes | £30M |
| | Life Systems Services 2 | Leeds | £30M |
| | Workforce Management System | Bicester | £30M |
| | NSSCOVID-19 -206 - 209 - Non Sterile Medical Examination Gloves | Edinburgh | £28M |
| | National Tutoring Programme Phase | London | £25M |
| | Advance Information Delivery Partner (ABC) | Croydon | £25M |
| | Grant Administration Services Framework | Glasgow | £25M |
| | Managed Service for Vehicle Recovery | North Wales | £25M |
| | Modular Modern-Methods of Construction Projects Framework Agreement | Stafford | £25M |
| | Secuirty Access Equipment | Reading | £25M |
| | Plymouth and Torbay Community Equipment Services | Plymouth | £24M |
| | Life Systems Services 2 | Leeds | £23M |
| | Appointment of a Contractor for a Residential Development at Grange Park, Blackpool, FY3 7PH | Blackpool | £22M |
| | Decontamination & Laundry Services | South Gloucestershire | £21M |
| | Global Workforce Mobility Services | Manchester | £20M |
| | Kitchens Windows and Doors — | Edinburgh | £20M |
| | Park Ops and Venues - Project Life Cycle Asset Replacement and Refurbishment Term Contracts | London | £19M |
| | Legal Services | London | £18M |