| | Commissioning Homes for Children Looked After and Care Leavers PDPS | London | £16B |
| | NHS National Generic Pharmaceuticals Wave 13 | Runcorn | £2B |
| | Housing Construction | Livingston | £2B |
| | Major Project Partnering Framework | Belfast | £1B |
| | Low Carbon Offsite MMC Construction - South West DPS | Exeter | £1B |
| | Low Carbon Offsite MMC Housing Construction - South West DPS | Exeter | £1B |
| | On-Site Surgical and Medical Capacity Solutions | Chester | £816M |
| | Schools and Community Buildings | Livingston | £800M |
| | NHS National Generic Pharmaceuticals Wave 13 | Runcorn | £711M |
| | Schools and Community Buildings — Wales | Uxbridge | £620M |
| | DPS for the Commissioning of Construction Consultancy Services | London | £550M |
| | Buckinghamshire Highways Service | Aylesbury | £540M |
| | National Collaborative Framework for Adult MH LD & CAMHS Hospital Services | Cardiff | £480M |
| | Variation Extension 09 | London | £424M |
| | Variation Extension 11 | London | £398M |
| | Disposable and Washable Continence Care and Associated Products | Sheffield | £395M |
| | DLR Rolling Stock Replacement Project - Manufacture and Supply Agreement | London | £346M |
| | Health and Disability Assessment Services (HDAS) | Sheffield | £300M |
| | Managed Solution Framework | London | £230M |
| | Aberdeen Hydrogen Hub Strategic Partnership | Aberdeen | £215M |
| | Adults & Children Including Learning Disability, Home Care, Extra Care & Related Services Framework Agreement | London | £180M |
| | Adults & Children Including Learning Disability, Home, Care, Extra Care & Related Services Framework Agreement | London | £180M |
| | CHIC Compliance Audit Services Framework | Birmingham | £150M |
| | Demolition Contractors Framework | Stockton on Tees | £150M |
| | Local Bus Services and School Bus Servics in Lancashire | Preston | £140M |
| | Framework–Services-Wastewater Drainage Area System Management | Warrington | £135M |
| | Personal Independence Payments (PIP) Assessment Service Extension - Lot 2 | Sheffield | £129M |
| | Combat Footwear | Bristol | £120M |
| | Trade Material Commodities and Associated Services to the City of Edinburgh Council | Edinburgh | £115M |
| | Acquisition, Design and Build Framework (ADB Framework) | London | £100M |
| | External Print and Digit Services | Birmingham | £100M |
| | Insulin Pumps, Continuous Glucose Monitoring, Closed Loop Insulin Delivery Systems and Associated Products | London | £100M |
| | National Diabetes Prevention Programme FW3 - PIN & Market Engagement | Runcorn | £100M |
| | Multidisciplinary Temporary Healthcare Personnel for Yorkshire & Lincolnshire NHS Trusts | Liverpool | £98M |
| | Third Party Telecommunications Systems | Birmingham | £97M |
| | Onsite Passenger Covid-19 Testing | Manchester | £96M |
| | Offices/Buildings - Planned and Reactive Maintenance | London | £95M |
| | FSA Delivered Official Controls in England and Wales | York | £87M |
| | HS2 Project Third Party Telecommunications Systems (Forming Part of Phase One and Phase 2a of the… | Birmingham | £81M |
| | Outdoor Playground, Fitness & Sports Facilities and Equipment (Design, Supply, Delivery, Installation, Maintenance and Inspection) | Leicester | £80M |
| | Market Engagement Event for Integrated Healthcare Services at HMP Onley, HMP Rye Hill and the New… | Mansfield | £78M |
| | FUTURE MARITIME SUPPORT PROGRAMME (FMSP) - FMSP/0010 Soft Facilities Management at Portsmouth Naval Base | London | £78M |
| | Responsive Capital Work | London | £75M |
| | Highways and Lighting Maintenance | Ilford | £71M |
| | Soft Facilities Management Services | London | £70M |
| | Soft Facilities Management Services for East London NHS Foundation Trust | London | £70M |
| | National Framework for Legal Services to Police Forces, Police and Crime Commissioners, and Other Eligible Public… | Greater London | £65M |
| | Hampden Road Lease | Kingston upon Thames | £58M |
| | Full Induction Programme Cohort of the National Roll-Out of the Early Career Framework | London | £56M |
| | Care and Support at Home Tier 1 Zones 5-7 - Fareham and Gosport | Winchester | £54M |
| | Childrens Public Health Nursing Service | Rotherham | £51M |
| | Childrens Public Health Nursing Service - Market Engagement - Soft Market Testing Exercise | Rotherham | £51M |
| | Vegetation Management Services | Milton Keynes | £50M |
| | Outdoor Playground, Fitness & Sports Facilities and Equipment (Design, Supply, Delivery, Installation, Maintenance and Inspection) | Leicester | £47M |
| | Metropolitan Police Construction Professional Services Framework | London | £40M |
| | Packaging and Soft Consumables | Bristol | £37M |
| | LBH Housebuilding Programme - Orchard Road, Everglades, Rose Gardens and Clements Court | Hounslow | £37M |
| | Pre-Flight Messaging Test Facility (PFMTF) Rigs and System Test Facility (STF) Rigs | Yeovil | £37M |
| | Bridges and Structures Framework | Hertfordshire | £36M |
| | Trades Contractors (2021 | Paisley | £35M |
| | ADC) Housing Refurbishment Partnership | Nottingham | £35M |
| | NHS Education With Kingston Hospital NHS Trust | Leeds | £31M |
| | NHS Education With Kingston Hospital NHS Trust | Leeds | £31M |
| | NHS Education With Tavistock and Portman NHS Foundation Trust | Leeds | £30M |
| | NHS Education With Tavistock and Portman NHS Foundation Trust | Leeds | £30M |
| | Home Group Repairs and Maintenance: Central Belt, Scotland | Newcastle upon Tyne | £30M |
| | Home Group Repairs and Maintenance: Dundee and Fife, Scotland | Newcastle upon Tyne | £30M |
| | Home Group Repairs & Maintenance: Dundee & Fife, Scotland | Newcastle upon Tyne | £30M |
| | Vehicle Recovery Services to Support the MPS Vehicle Recovery & Examination Services (VRES) Operations | London | £30M |
| | Life Systems Services 2 | Leeds | £30M |
| | NHS Education With Croydon Health Services NHS Trust | Leeds | £30M |
| | NHS Education With Croydon Health Services NHS Trust | Leeds | £30M |
| | Emergency Towing Vessel (ETV) | Southampton | £29M |
| | Global Airline Partner Framework Agreement | London | £27M |
| | Telemetry Engineering Support Services | Glasgow | £27M |
| | Appointment of a Contractor for a Residential Development at Grange Park, Blackpool, FY3 7PH | Blackpool | £26M |
| | National Quantum Computing Centre (NQCC) - PCSA & Main Contractor | Swindon | £22M |
| | Southampton Improving Access to Psychological Therapies (IAPT) Service | Winchester | £22M |
| | Joint Venture Development Partner for Astmoor Regeneration | Widnes | £22M |
| | Ground Maintenance Services to British High Commission, New Delhi | London | £22M |
| | Communal Cleaning and Grounds Maintenance Services | London | £21M |
| | Heavy Lift Challenge | Bristol | £20M |
| | Highways & Civil Engineering Materials | Newcastle upon Tyne | £20M |
| | Household Waste Recycling Centre (HWRC) and Waste Transfer Station (WTS) Middlemore Lane, Aldridge Construction and Fryers… | Walsall | £20M |
| | Covid-19: DHSC: Renal Replacement Therapy (RRT) Stockpile | London | £19M |
| | Delivering Core Services to Improve Support Offered to Children and Young People With SEND and Their… | London | £19M |
| | Cat D Prison Expansion Programme (HMP Standford Hill) | London | £19M |
| | European Social Fund Provision 2014-20 (Skills Support to the Unemployed, Support for Young People Who Are… | Coventry | £18M |
| | Ductile Iron Pipe and Fittings | Glasgow | £18M |
| | CM88a TSC for Gas and Solid Fuel Servicing, Repairs, Call Out and Central Heating Installation | Beverley | £17M |
| | NHS Education With West London NHS Trust | Leeds | £17M |
| | NHS Education With West London NHS Trust | Leeds | £17M |
| | Any Qualified Provider for Adult Hearing for Greater Manchester CCGs | Greater Manchester | £15M |
| | Publishing for the English Heritage Members' Magazine and Podcast | Wiltshire | £15M |
| | Publishing for the English Heritage Members’ Magazine and Podcast | Swindon | £15M |
| | Cat D Prison Expansion Programme (HMP Sudbury) | London | £15M |
| | NHS Education With Oxleas NHS Foundation Trust | Leeds | £14M |
| | NHS Education With Oxleas NHS Foundation Trust | Leeds | £14M |
| | Cat D Prison Expansion Programme (HMP Ford) | London | £14M |
| | Protection Services | West Midlands | £14M |